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Found 394 with Last Name = 'liégeois' and Initial = 'jf'
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM86708(CAS_146714-97-8 | CHEMBL31354 | CHEMBL514874 | CHE...)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5-HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50395206(CHEMBL2164354)
Affinity DataKi:  0.510nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5-HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50040237(2-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f]...)
Affinity DataKi:  0.600nMAssay Description:In vitro binding affinity against rat 5-hydroxytryptamine 2 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50395206(CHEMBL2164354)
Affinity DataKi:  0.690nMAssay Description:Binding affinity to 5HT1A receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  0.870nMAssay Description:Binding affinity against dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  0.880nMAssay Description:In vitro binding affinity against Dopamine D2 receptor in rat striatal tissue.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50395207(CHEMBL2164350)
Affinity DataKi:  1.21nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5-HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50395216(CHEMBL2164347)
Affinity DataKi:  1.61nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5-HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50324887(CHEMBL1221498 | N-(2-(4-(2-methoxyphenyl)piperazin...)
Affinity DataKi:  1.69nMAssay Description:Displacement of [3H]MK912 from human alpha2A receptor after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM22870(13-chloro-10-(piperazin-1-yl)-2-oxa-9-azatricyclo[...)
Affinity DataKi:  1.77nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5HT2A receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50010594(2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  1.80nMAssay Description:In vitro binding affinity against rat 5-hydroxytryptamine 2 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50395207(CHEMBL2164350)
Affinity DataKi:  1.85nMAssay Description:Binding affinity to 5HT1A receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50395215(CHEMBL2164348)
Affinity DataKi:  1.89nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5-HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataKi:  2nMAssay Description:Binding affinity against dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataKi:  2nMAssay Description:In vitro binding affinity against Dopamine D2 receptor in rat striatal tissue.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50403770(CHEMBL12427)
Affinity DataKi:  2.10nMAssay Description:Binding affinity to 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  2.20nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D4 expressed in Sf9 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50324887(CHEMBL1221498 | N-(2-(4-(2-methoxyphenyl)piperazin...)
Affinity DataKi:  2.32nMAssay Description:Displacement of [3H]8OH-DPAT from human 5HT1A receptor after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM22871(13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azat...)
Affinity DataKi:  2.42nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5HT2A receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50395214(CHEMBL2164349)
Affinity DataKi:  2.48nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5-HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50119380(CHEMBL25236 | CHEMBL540612 | N-(4-(4-(2-methoxyphe...)
Affinity DataKi:  2.75nMAssay Description:Displacement of [3H]MK912 from human alpha2A receptor after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50324894(CHEMBL1221594 | N-(6-(4-(2-methoxyphenyl)piperazin...)
Affinity DataKi:  2.87nMAssay Description:Displacement of [3H]MK912 from human alpha2A receptor after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataKi:  3.30nMAssay Description:In vitro binding affinity against rat 5-hydroxytryptamine 2 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50116963(2a-(4-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)butyl)...)
Affinity DataKi:  3.30nMAssay Description:Binding affinity to 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataKi:  3.80nMAssay Description:In vitro binding affinity against rat 5-hydroxytryptamine 2 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50040241(3-Fluoro-6-(4-methyl-piperazin-1-yl)-11H-dibenzo[b...)
Affinity DataKi:  3.80nMAssay Description:In vitro binding affinity against rat 5-hydroxytryptamine 2 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50040243(8-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f]...)
Affinity DataKi:  4.10nMAssay Description:In vitro binding affinity against rat 5-hydroxytryptamine 2 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50324890(CHEMBL1221545 | N-(4-(4-(2-methoxyphenyl)piperazin...)
Affinity DataKi:  4.10nMAssay Description:Displacement of [3H]MK912 from human alpha2A receptor after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50040237(2-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f]...)
Affinity DataKi:  4.40nMAssay Description:In vitro binding affinity against Dopamine D2 receptor in rat striatal tissue.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50040237(2-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f]...)
Affinity DataKi:  4.5nMAssay Description:Binding affinity against dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50324889(CHEMBL1221544 | N-(3-(4-(2-methoxyphenyl)piperazin...)
Affinity DataKi:  4.59nMAssay Description:Displacement of [3H]MK912 from human alpha2A receptor after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50261126(CHEMBL497749 | N-(3-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  4.64nMAssay Description:Displacement of [3H]MK912 from human alpha2A receptor after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataKi:  4.84nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5HT2A receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50324888(CHEMBL1221499 | N-(2-(4-(2-methoxyphenyl)piperazin...)
Affinity DataKi:  5.19nMAssay Description:Displacement of [3H]MK912 from human alpha2A receptor after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50040243(8-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f]...)
Affinity DataKi:  5.60nMAssay Description:In vitro binding affinity against Muscarinic acetylcholine receptors in rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50324893(CHEMBL1221593 | N-(6-(4-(2-methoxyphenyl)piperazin...)
Affinity DataKi:  6.15nMAssay Description:Displacement of [3H]MK912 from human alpha2A receptor after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50040250(8-Chloro-6-(4-methyl-piperazin-1-yl)-11H-benzo[e]p...)
Affinity DataKi:  6.20nMAssay Description:In vitro binding affinity against rat 5-hydroxytryptamine 2 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataKi:  6.70nMAssay Description:In vitro binding affinity at serotonin 5-hydroxytryptamine 2A receptor in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50395208(CHEMBL2164346)
Affinity DataKi:  8.27nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5-HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50395210(CHEMBL2164355)
Affinity DataKi:  8.36nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5-HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  8.5nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D2L expressed in Sf9 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50324892(CHEMBL1221592 | N-(5-(4-(2-methoxyphenyl)piperazin...)
Affinity DataKi:  8.53nMAssay Description:Displacement of [3H]MK912 from human alpha2A receptor after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM22871(13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azat...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]-YM09151-2 from human cloned dopamine D4 receptor expressed in insect Sf9 cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50324891(CHEMBL1221591 | N-(5-(4-(2-methoxyphenyl)piperazin...)
Affinity DataKi:  9.36nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50324894(CHEMBL1221594 | N-(6-(4-(2-methoxyphenyl)piperazin...)
Affinity DataKi:  9.62nMAssay Description:Displacement of [3H]8OH-DPAT from human 5HT1A receptor after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50203383(CHEMBL228972 | N-(1-benzylpiperidin-4-yl)-2-naphth...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]nemonapride from human cloned dopamine D4.2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50203383(CHEMBL228972 | N-(1-benzylpiperidin-4-yl)-2-naphth...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]nemonapride from human cloned dopamine D4.2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50203374(CHEMBL234825 | naphthalene-2-carboxylic acid [1-(3...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]nemonapride from human cloned dopamine D4.2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50324891(CHEMBL1221591 | N-(5-(4-(2-methoxyphenyl)piperazin...)
Affinity DataKi:  11.1nMAssay Description:Displacement of [3H]MK912 from human alpha2A receptor after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50010594(2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  13nMAssay Description:In vitro binding affinity against Dopamine D2 receptor in rat striatal tissue.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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