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Found 113 with Last Name = 'lightle' and Initial = 's'
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50200120(CHEMBL260091 | CHIR-090 | US10875832, Compound ChI...)
Affinity DataKi:  2nMAssay Description:Inhibition of Escherichia coli LpxCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50478376(BB-78485 | CHEMBL261713)
Affinity DataKi:  20nMAssay Description:Inhibition of Escherichia coli LpxCMore data for this Ligand-Target Pair
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50074960((R)-2-(3,4-Dimethoxy-5-propyl-phenyl)-4,5-dihydro-...)
Affinity DataKi:  50nMAssay Description:Inhibition of Escherichia coli LpxCMore data for this Ligand-Target Pair
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483375(CHEMBL1236446)
Affinity DataKi:  650nMAssay Description:Inhibition of Escherichia coli LpxCMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50484911(CHEMBL2012204)
Affinity DataIC50:  0.376nMAssay Description:Inhibition of Pseudomonas aeruginosa LpxCMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50484910(CHEMBL2012200)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of Pseudomonas aeruginosa LpxCMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50484904(CHEMBL2012203)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of Pseudomonas aeruginosa LpxCMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483411(CHEMBL1668464)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of Escherichia coli LpxCMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50484896(CHEMBL2012205)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of Pseudomonas aeruginosa LpxCMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50484916(CHEMBL2012199)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of Pseudomonas aeruginosa LpxCMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50484895(CHEMBL2012202)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of Pseudomonas aeruginosa LpxCMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBiotin carboxylase(Escherichia coli (strain K12))
Pfizer

LigandPNGBDBM3436(6-(2,6-Dibromo-phenyl)-pyrido[2,3-d]pyrimidine-2,7...)
Affinity DataIC50: <1nMpH: 8.0 T: 2°CAssay Description:Assays were performed in 384-well clear bottom plates (Corning; catalog no. 3702), that contained inhibitor solvated in DMSO. To each well of the pla...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50491647(CHEMBL2387019)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of PDE4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50491689(CHEMBL2387425)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50491682(CHEMBL2387423)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50491698(CHEMBL2387426)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50491681(CHEMBL2387427)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50491680(CHEMBL2387429)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50491693(CHEMBL2387428)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50484894(CHEMBL2012201)
Affinity DataIC50:  3nMAssay Description:Inhibition of Pseudomonas aeruginosa LpxCMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50484917(CHEMBL2012187)
Affinity DataIC50:  3nMAssay Description:Inhibition of Pseudomonas aeruginosa LpxCMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50484899(CHEMBL2012186)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of Pseudomonas aeruginosa LpxCMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50491679(CHEMBL2387430 | US11419874, Example 3)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50491694(CHEMBL2385104)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50484900(CHEMBL2012188)
Affinity DataIC50:  4nMAssay Description:Inhibition of Pseudomonas aeruginosa LpxCMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50491651(CHEMBL2387143)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of PDE2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50491699(CHEMBL2387422)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50491690(CHEMBL2387441)
Affinity DataIC50:  7nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBiotin carboxylase(Escherichia coli (strain K12))
Pfizer

LigandPNGBDBM32642(amino-oxazole, 2d)
Affinity DataIC50:  7nMpH: 8.0 T: 2°CAssay Description:Assays were performed in 384-well clear bottom plates (Corning; catalog no. 3702), that contained inhibitor solvated in DMSO. To each well of the pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50484907(CHEMBL2012182)
Affinity DataIC50:  8nMAssay Description:Inhibition of Pseudomonas aeruginosa LpxCMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50484901(CHEMBL2012189)
Affinity DataIC50:  8nMAssay Description:Inhibition of Pseudomonas aeruginosa LpxCMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50491697(CHEMBL2387424)
Affinity DataIC50:  9.30nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50491692(CHEMBL2387436)
Affinity DataIC50:  14nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50484909(CHEMBL2012196)
Affinity DataIC50:  15nMAssay Description:Inhibition of Pseudomonas aeruginosa LpxCMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50484906(CHEMBL2012195)
Affinity DataIC50:  18nMAssay Description:Inhibition of Pseudomonas aeruginosa LpxCMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50491683(CHEMBL2387440)
Affinity DataIC50:  18nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50484913(CHEMBL2012185)
Affinity DataIC50:  22nMAssay Description:Inhibition of Pseudomonas aeruginosa LpxCMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50491645(CHEMBL2387135)
Affinity DataIC50:  23nMAssay Description:Inhibition of PDE2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50484915(CHEMBL2012198)
Affinity DataIC50:  25nMAssay Description:Inhibition of Pseudomonas aeruginosa LpxCMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50484893(CHEMBL2012197)
Affinity DataIC50:  26nMAssay Description:Inhibition of Pseudomonas aeruginosa LpxCMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50484914(CHEMBL2012193)
Affinity DataIC50:  28nMAssay Description:Inhibition of Pseudomonas aeruginosa LpxCMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50491650(CHEMBL2387020)
Affinity DataIC50:  31nMAssay Description:Inhibition of PDE4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50491684(CHEMBL2387439)
Affinity DataIC50:  36nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50491695(CHEMBL2387437)
Affinity DataIC50:  40nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50491644(CHEMBL2387139)
Affinity DataIC50:  44nMAssay Description:Inhibition of PDE2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50491643(CHEMBL2387140)
Affinity DataIC50:  45nMAssay Description:Inhibition of PDE2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50491643(CHEMBL2387140)
Affinity DataIC50:  45nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50491685(CHEMBL2387435)
Affinity DataIC50:  46nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50491645(CHEMBL2387135)
Affinity DataIC50:  48nMAssay Description:Inhibition of PDE4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50484903(CHEMBL2012194)
Affinity DataIC50:  51nMAssay Description:Inhibition of Pseudomonas aeruginosa LpxCMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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