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Found 403 with Last Name = 'ma' and Initial = 'ly'
TargetDCN1-like protein 1(Homo sapiens)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50584167(CHEMBL5085822)
Affinity DataKi:  8.30nMAssay Description:Binding affinity to DCN1 (unknown origin) assessed as inhibitory constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50525313(CHEMBL4592844)
Affinity DataKi:  14nMAssay Description:Binding affinity to DCN1 (unknown origin) assessed as inhibitory constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDCN1-like protein 4(Homo sapiens)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50525313(CHEMBL4592844)
Affinity DataKi:  810nMAssay Description:Binding affinity to DCN4 (unknown origin) assessed as inhibitory constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDCN1-like protein 5(Homo sapiens)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50525313(CHEMBL4592844)
Affinity DataKi:  2.14E+3nMAssay Description:Binding affinity to DCN5 (unknown origin) assessed as inhibitory constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDCN1-like protein 2(Homo sapiens)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50584167(CHEMBL5085822)
Affinity DataKi:  1.88E+4nMAssay Description:Binding affinity to DCN2 (unknown origin) assessed as inhibitory constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 4(Homo sapiens)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50584167(CHEMBL5085822)
Affinity DataKi:  2.24E+4nMAssay Description:Binding affinity to DCN4 (unknown origin) assessed as inhibitory constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 5(Homo sapiens)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50584167(CHEMBL5085822)
Affinity DataKi:  2.89E+4nMAssay Description:Binding affinity to DCN5 (unknown origin) assessed as inhibitory constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 2(Homo sapiens)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50525313(CHEMBL4592844)
Affinity DataKi:  6.62E+4nMAssay Description:Binding affinity to DCN2 (unknown origin) assessed as inhibitory constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDCN1-like protein 3(Homo sapiens)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50584167(CHEMBL5085822)
Affinity DataKi:  3.85E+5nMAssay Description:Binding affinity to DCN3 (unknown origin) assessed as inhibitory constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 3(Homo sapiens)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50525313(CHEMBL4592844)
Affinity DataKi:  5.92E+5nMAssay Description:Binding affinity to DCN3 (unknown origin) assessed as inhibitory constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Key Laboratory Of Technology Of Drug Preparation (Zhengzhou University)

Curated by ChEMBL
LigandPNGBDBM50589142(CHEMBL5184459)
Affinity DataIC50:  0.0190nMAssay Description:Inhibition of human recombinant c-MET in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Key Laboratory Of Technology Of Drug Preparation (Zhengzhou University)

Curated by ChEMBL
LigandPNGBDBM50589150(CHEMBL5189340)
Affinity DataIC50:  0.0230nMAssay Description:Inhibition of VEGFR-2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Key Laboratory Of Technology Of Drug Preparation (Zhengzhou University)

Curated by ChEMBL
LigandPNGBDBM50589141(CHEMBL5174958)
Affinity DataIC50:  0.0350nMAssay Description:Inhibition of human recombinant c-MET in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Key Laboratory Of Technology Of Drug Preparation (Zhengzhou University)

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  0.0600nMAssay Description:Inhibition of VEGFR2 (unknown origin) using ULight-4E-BP1 peptide as substrate incubated for 1 hr in presence of ATP by fluorescence based analysisMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587720(CHEMBL5195946)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of full length human recombinant HDAC6 incubated for 30 to 60 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Key Laboratory Of Technology Of Drug Preparation (Zhengzhou University)

Curated by ChEMBL
LigandPNGBDBM50589147(CHEMBL5186748)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of VEGFR2 (unknown origin) using ULight-4E-BP1 peptide as substrate incubated for 1 hr in presence of ATP by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDCN1-like protein 1(Homo sapiens)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50525311(CHEMBL4448070)
Affinity DataIC50:  0.25nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587716(CHEMBL5188297)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of recombinant full length HDAC6 (unknown origin) using fluorophore conjugated substrate by microplate reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Key Laboratory Of Technology Of Drug Preparation (Zhengzhou University)

Curated by ChEMBL
LigandPNGBDBM50589150(CHEMBL5189340)
Affinity DataIC50:  0.450nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Key Laboratory Of Technology Of Drug Preparation (Zhengzhou University)

Curated by ChEMBL
LigandPNGBDBM50589140(CHEMBL5190707)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of c-MET (unknown origin) using FAM-labelled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Key Laboratory Of Technology Of Drug Preparation (Zhengzhou University)

Curated by ChEMBL
LigandPNGBDBM50589144(CHEMBL5208686)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of VEGFR2 (unknown origin) using ULight-4E-BP1 peptide as substrate incubated for 1 hr in presence of ATP by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Key Laboratory Of Technology Of Drug Preparation (Zhengzhou University)

Curated by ChEMBL
LigandPNGBDBM50589145(CHEMBL5177149)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of VEGFR2 (unknown origin) using ULight-4E-BP1 peptide as substrate incubated for 1 hr in presence of ATP by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM417049(4-((6-chloro-3,4-dihydroquinolin-1(2H)-yl)methyl)-...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of full length human recombinant HDAC6 using RHKKAc-AMC fluorogenic peptide as substrate incubated for 2 hrs by microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDCN1-like protein 1(Homo sapiens)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50584177(CHEMBL5076401)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Key Laboratory Of Technology Of Drug Preparation (Zhengzhou University)

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human full length PARP1 expressed in Escherichia coli rosetta (DE3) incubated for 20 mins by fluorescence analysisMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM110036(US8609678, 2-((2-chlorophenyl)(phenyl)amino)-N-(7-...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of HDAC6 (unknown origin) using FTS as substrate preincubated for 10 mins followed by substrate addition by microtiter plate reader assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Key Laboratory Of Technology Of Drug Preparation (Zhengzhou University)

Curated by ChEMBL
LigandPNGBDBM50288530(CHEMBL4098253)
Affinity DataIC50:  2.80nMAssay Description:Displacement of [125I]KX1 from PARP1 in human OVCAR-8 cells incubated for 1 hr by wizard gamma counter analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Key Laboratory Of Technology Of Drug Preparation (Zhengzhou University)

Curated by ChEMBL
LigandPNGBDBM50589143(CHEMBL5174011)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of human full length PARP1 expressed in Escherichia coli rosetta (DE3) incubated for 20 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDCN1-like protein 1(Homo sapiens)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50584172(CHEMBL5075399)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587718(CHEMBL5185889)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using RHKKAc-AMC fluorogenic substrate by microtiter plate reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Key Laboratory Of Technology Of Drug Preparation (Zhengzhou University)

Curated by ChEMBL
LigandPNGBDBM50589154(CHEMBL5176058)
Affinity DataIC50:  4.20nMAssay Description:Displacement of [125I]KX1 from PARP1 in human OVCAR-8 cells incubated for 1 hr by wizard gamma counter analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Key Laboratory Of Technology Of Drug Preparation (Zhengzhou University)

Curated by ChEMBL
LigandPNGBDBM50589155(CHEMBL5196674)
Affinity DataIC50:  4.70nMAssay Description:Displacement of [125I]KX1 from PARP1 in human OVCAR-8 cells incubated for 1 hr by wizard gamma counter analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50439674(RICOLINOSTAT | US10858323, Compound 2 | US11207431...)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of HDAC6 (unknown origin) using FTS as substrate preincubated for 10 mins followed by substrate addition by microtiter plate reader assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDCN1-like protein 1(Homo sapiens)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50584163(CHEMBL5070367)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50584157(CHEMBL5091659)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50584169(CHEMBL5092564)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50562487(CHEMBL4757504)
Affinity DataIC50:  6.90nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Key Laboratory Of Technology Of Drug Preparation (Zhengzhou University)

Curated by ChEMBL
LigandPNGBDBM50589152(CHEMBL5179574)
Affinity DataIC50:  7nMAssay Description:Inhibition of PARP1 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587722(CHEMBL5173000)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of full length human recombinant HDAC6 expressed in baculovirus infected Sf9 cells using RHKKAc fluorogenic peptide as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Key Laboratory Of Technology Of Drug Preparation (Zhengzhou University)

Curated by ChEMBL
LigandPNGBDBM50589153(CHEMBL5185911)
Affinity DataIC50:  8.20nMAssay Description:Displacement of [125I]KX1 from PARP1 in human OVCAR-8 cells incubated for 1 hr by wizard gamma counter analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587716(CHEMBL5188297)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of recombinant full length HDAC1 (unknown origin) using fluorophore conjugated substrate by microplate reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50562134(CHEMBL4794518)
Affinity DataIC50:  8.80nMAssay Description:Inhibition of N-terminal His-tagged p300 HAT (unknown origin) (1287 to 1666 residues) expressed in Escherichia coli using biotinylated H3(1-21) pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50584179(CHEMBL5086499)
Affinity DataIC50:  9.40nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50584167(CHEMBL5085822)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50584170(CHEMBL5082310)
Affinity DataIC50:  11nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM195608(CPI-455)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged KDM5B expressed in Sf9 insect cells using biotin-H3K4me as substrate by ALPHAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50584160(CHEMBL5078162)
Affinity DataIC50:  11nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50562491(CHEMBL4744710)
Affinity DataIC50:  12nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Key Laboratory Of Technology Of Drug Preparation (Zhengzhou University)

Curated by ChEMBL
LigandPNGBDBM50589157(CHEMBL5180625)
Affinity DataIC50:  12nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDCN1-like protein 1(Homo sapiens)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50584178(CHEMBL5091608)
Affinity DataIC50:  12nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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