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Found 46 with Last Name = 'motabar' and Initial = 'o'
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50068039(1-{3-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Affinity DataKi:  17nMAssay Description:Binding affinity to human SST4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50496732(CHEMBL1591268)
Affinity DataKi:  19nMAssay Description:Binding affinity to human SST4 receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50496735(CHEMBL1355048)
Affinity DataKi:  26nMAssay Description:Binding affinity to human SST4 receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50496733(CHEMBL1591395)
Affinity DataKi:  160nMAssay Description:Binding affinity to human SST4 receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50496734(CHEMBL1590268)
Affinity DataKi:  690nMAssay Description:Binding affinity to human SST4 receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
National Center For Advancing Translation Sciences

Curated by ChEMBL
LigandPNGBDBM50182801((3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol, 8...)
Affinity DataIC50:  30nMAssay Description:Inhibition of wild type glucocerebrosidase using 4-methylumbellifereno-Glc as substrate incubated for 5 mins prior to substrate addition measured aft...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
National Center For Advancing Translation Sciences

Curated by ChEMBL
LigandPNGBDBM18428(Aminoquinoline compound, 1 | N-[4-methyl-2-(morpho...)
Affinity DataIC50:  30nMAssay Description:Inhibition of wild type glucocerebrosidase using 4-methylumbellifereno-Glc as substrate incubated for 5 mins prior to substrate addition measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
National Center For Advancing Translation Sciences

Curated by ChEMBL
LigandPNGBDBM18438(4-benzenesulfonamido-N-(5-ethyl-1,3,4-thiadiazol-2...)
Affinity DataIC50:  100nMAssay Description:Inhibition of wild type glucocerebrosidase using 4-methylumbellifereno-Glc as substrate incubated for 5 mins prior to substrate addition measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
National Center For Advancing Translation Sciences

Curated by ChEMBL
LigandPNGBDBM50396168(CHEMBL1361379)
Affinity DataIC50:  280nMAssay Description:Inhibition of wild type glucocerebrosidase in human spleen homogenate using 4-methylumbellifereno-Glc as substrate incubated for 5 mins prior to subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
National Center For Advancing Translation Sciences

Curated by ChEMBL
LigandPNGBDBM50068039(1-{3-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Affinity DataIC50:  360nMAssay Description:Inhibition of wild type glucocerebrosidase in human spleen homogenate using 4-methylumbellifereno-Glc as substrate incubated for 5 mins prior to subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
National Center For Advancing Translation Sciences

Curated by ChEMBL
LigandPNGBDBM18447(2-({4-[(5-chloro-2-methoxyphenyl)amino]-6-(pyrroli...)
Affinity DataIC50:  400nMAssay Description:Inhibition of wild type glucocerebrosidase using 4-methylumbellifereno-Glc as substrate incubated for 5 mins prior to substrate addition measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
National Center For Advancing Translation Sciences

Curated by ChEMBL
LigandPNGBDBM50068039(1-{3-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Affinity DataIC50:  710nMAssay Description:Inhibition of wild type glucocerebrosidase using 4-methylumbellifereno-Glc as substrate incubated for 5 mins prior to substrate addition measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398032(CHEMBL1603014)
Affinity DataIC50:  750nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using blue-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398032(CHEMBL1603014)
Affinity DataIC50:  940nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using red-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398022(CHEMBL2181097)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using blue-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398022(CHEMBL2181097)
Affinity DataIC50:  1.46E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using red-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398020(CHEMBL2181103)
Affinity DataIC50:  1.63E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using blue-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398020(CHEMBL2181103)
Affinity DataIC50:  1.63E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using red-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398029(CHEMBL2180814)
Affinity DataIC50:  1.88E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using blue-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
National Center For Advancing Translation Sciences

Curated by ChEMBL
LigandPNGBDBM18428(Aminoquinoline compound, 1 | N-[4-methyl-2-(morpho...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of wild type glucocerebrosidase in human spleen homogenate using 4-methylumbellifereno-Glc as substrate incubated for 5 mins prior to subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398029(CHEMBL2180814)
Affinity DataIC50:  2.37E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using red-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398028(CHEMBL2180816)
Affinity DataIC50:  2.91E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using blue-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
National Center For Advancing Translation Sciences

Curated by ChEMBL
LigandPNGBDBM18438(4-benzenesulfonamido-N-(5-ethyl-1,3,4-thiadiazol-2...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of wild type glucocerebrosidase in human spleen homogenate using 4-methylumbellifereno-Glc as substrate incubated for 5 mins prior to subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398028(CHEMBL2180816)
Affinity DataIC50:  3.26E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using red-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398027(CHEMBL2181089)
Affinity DataIC50:  3.26E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using red-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398027(CHEMBL2181089)
Affinity DataIC50:  3.66E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using blue-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398024(CHEMBL2181095)
Affinity DataIC50:  3.66E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using blue-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398024(CHEMBL2181095)
Affinity DataIC50:  4.11E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using red-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
National Center For Advancing Translation Sciences

Curated by ChEMBL
LigandPNGBDBM18447(2-({4-[(5-chloro-2-methoxyphenyl)amino]-6-(pyrroli...)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of wild type glucocerebrosidase in human spleen homogenate using 4-methylumbellifereno-Glc as substrate incubated for 5 mins prior to subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
National Center For Advancing Translation Sciences

Curated by ChEMBL
LigandPNGBDBM50396168(CHEMBL1361379)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibition of wild type glucocerebrosidase using 4-methylumbellifereno-Glc as substrate incubated for 5 mins prior to substrate addition measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398031(CHEMBL1708234)
Affinity DataIC50:  1.19E+4nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using blue-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398021(CHEMBL2181098)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using red-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398021(CHEMBL2181098)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using blue-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398031(CHEMBL1708234)
Affinity DataIC50:  1.49E+4nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using red-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398025(CHEMBL2181094)
Affinity DataIC50:  1.49E+4nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using blue-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398025(CHEMBL2181094)
Affinity DataIC50:  1.49E+4nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using red-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398030(CHEMBL2180813)
Affinity DataIC50:  1.88E+4nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using red-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398030(CHEMBL2180813)
Affinity DataIC50:  2.37E+4nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using blue-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398023(CHEMBL2181096)
Affinity DataIC50:  2.59E+4nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using blue-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398019(CHEMBL1892795)
Affinity DataIC50:  3.26E+4nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using blue-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398023(CHEMBL2181096)
Affinity DataIC50:  3.66E+4nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using red-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398019(CHEMBL1892795)
Affinity DataIC50:  4.11E+4nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using red-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398026(CHEMBL2181091)
Affinity DataIC50:  9.43E+4nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using blue-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398026(CHEMBL2181091)
Affinity DataIC50:  9.43E+4nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using red-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398020(CHEMBL2181103)
Affinity DataKd:  2.00E+4nMAssay Description:Binding affinity at wild type recombinant NT-495 labelled GAA incubated for 15 mins by microscale thermophoresis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398032(CHEMBL1603014)
Affinity DataKd:  2.00E+4nMAssay Description:Binding affinity at wild type recombinant NT-495 labelled GAA incubated for 15 mins by microscale thermophoresis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed