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Found 31 with Last Name = 'opperdoes' and Initial = 'f'
TargetPhosphotransferase(Trypanosoma brucei)
Universite Paul Sabatier

LigandPNGBDBM43835(Glucosamine derivative, 8 | MLS000582359 | N-cyclo...)
Affinity DataKi:  2.80E+3nM ΔG°:  -31.7kJ/mole IC50:  5.00E+5nMT: 2°CAssay Description:Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphotransferase(Trypanosoma brucei)
Universite Paul Sabatier

LigandPNGBDBM43833(2-hydroxy-N''''-(3-keto-5,5-dimethyl-cyclohexen-1-...)
Affinity DataKi:  8.00E+3nM ΔG°:  -29.1kJ/mole IC50:  2.00E+6nMT: 2°CAssay Description:Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphotransferase(Trypanosoma brucei)
Universite Paul Sabatier

LigandPNGBDBM43832(2-phenylcyclopropane-1,1-dicarboxylic acid diethyl...)
Affinity DataKi:  1.90E+4nM ΔG°:  -26.9kJ/mole IC50:  4.00E+5nMT: 2°CAssay Description:Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphotransferase(Trypanosoma brucei)
Universite Paul Sabatier

LigandPNGBDBM43834(2-methoxy-4-[[4-(4-methylphenyl)-1-piperazinyl]met...)
Affinity DataKi:  2.50E+4nM ΔG°:  -26.3kJ/mole IC50:  3.00E+6nMT: 2°CAssay Description:Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphotransferase(Trypanosoma brucei)
Universite Paul Sabatier

LigandPNGBDBM43838(4-O-[5-bromo-2-cyclopropyl-3-(4-methoxyphenyl)-7-m...)
Affinity DataKi:  3.00E+4nM ΔG°:  -25.8kJ/mole IC50:  3.00E+6nMT: 2°CAssay Description:Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphotransferase(Trypanosoma brucei)
Universite Paul Sabatier

LigandPNGBDBM43837((4S,5R,6R)-1-(2-ethoxy-2-keto-ethyl)-2-keto-6-meth...)
Affinity DataKi:  7.00E+4nM ΔG°:  -23.7kJ/mole IC50:  3.00E+6nMT: 2°CAssay Description:Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphotransferase(Trypanosoma brucei)
Universite Paul Sabatier

LigandPNGBDBM43836(Glucosamine derivative, 9 | MLS000580208 | N-(2,5-...)
Affinity DataKi:  1.00E+5nM ΔG°:  -22.8kJ/mole IC50:  4.00E+6nMT: 2°CAssay Description:Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphotransferase(Trypanosoma brucei)
Universite Paul Sabatier

LigandPNGBDBM43829(Glucosamine derivative, 2 | MLS000568543 | SMR0001...)
Affinity DataKi:  1.00E+5nM ΔG°:  -22.8kJ/mole IC50:  6.00E+6nMT: 2°CAssay Description:Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphotransferase(Trypanosoma brucei)
Universite Paul Sabatier

LigandPNGBDBM43830(5-(amoxymethyl)-3-[2-[(4-phenylthiazol-2-yl)hydraz...)
Affinity DataKi:  1.05E+5nM ΔG°:  -22.7kJ/mole IC50:  4.50E+6nMT: 2°CAssay Description:Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphotransferase(Trypanosoma brucei)
Universite Paul Sabatier

LigandPNGBDBM43831(5-(4-fluorobenzyl)-4-keto-6,7-dihydropyrazolo[1,5-...)
Affinity DataKi:  1.14E+5nM ΔG°:  -22.5kJ/mole IC50:  1.80E+6nMT: 2°CAssay Description:Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50030947(CHEMBL331845 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Affinity DataIC50:  300nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of Leishmania mexicanaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50030949((2R,3R,4S,5R)-2-(6-Amino-8-thiophen-2-yl-purin-9-y...)
Affinity DataIC50:  500nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of Leishmania mexicanaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50030949((2R,3R,4S,5R)-2-(6-Amino-8-thiophen-2-yl-purin-9-y...)
Affinity DataIC50:  600nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyd 3-phosphate dehydrogenase (gGAPDH) of Trypanosoma bruceiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50030949((2R,3R,4S,5R)-2-(6-Amino-8-thiophen-2-yl-purin-9-y...)
Affinity DataIC50:  1.30E+3nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of human erythrocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50030947(CHEMBL331845 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Affinity DataIC50:  2.20E+3nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of Trypanosoma bruceiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50037775(CHEMBL121204 | Thiophene-2-carboxylic acid [2-(6-a...)
Affinity DataIC50:  2.40E+3nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of Leishmania mexicanaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50037777(CHEMBL120653 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Affinity DataIC50:  3.30E+3nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of Leishmania mexicanaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50037775(CHEMBL121204 | Thiophene-2-carboxylic acid [2-(6-a...)
Affinity DataIC50:  5.00E+3nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of Trypanosoma bruceiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50037777(CHEMBL120653 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Affinity DataIC50:  6.00E+3nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of Trypanosoma bruceiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50368901(CHEMBL608348)
Affinity DataIC50:  6.00E+3nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of Leishmania mexicanaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50368901(CHEMBL608348)
Affinity DataIC50:  8.00E+3nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of Trypanosoma bruceiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50030947(CHEMBL331845 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of human erythrocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50422031(8-Phenyladenosine | CHEMBL1775010)
Affinity DataIC50:  1.00E+4nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of Trypanosoma bruceiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50422031(8-Phenyladenosine | CHEMBL1775010)
Affinity DataIC50:  1.00E+4nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of human erythrocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50037777(CHEMBL120653 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of human erythrocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50368901(CHEMBL608348)
Affinity DataIC50: >1.00E+4nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of human erythrocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50037775(CHEMBL121204 | Thiophene-2-carboxylic acid [2-(6-a...)
Affinity DataIC50: >1.00E+4nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of human erythrocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM14487((2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxy...)
Affinity DataIC50:  3.50E+4nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of human erythrocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM14487((2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxy...)
Affinity DataIC50:  5.00E+4nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of Leishmania mexicanaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM14487((2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxy...)
Affinity DataIC50:  1.00E+5nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of Trypanosoma bruceiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphotransferase(Trypanosoma brucei)
Universite Paul Sabatier

LigandPNGBDBM43828(2-[(4-fluorobenzyl)thio]-N-(4,5,6,7-tetrahydro-1,3...)
Affinity DataIC50:  8.00E+6nMT: 2°CAssay Description:Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed