TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University
Curated by ChEMBL
Sun Yat-Sen University
Curated by ChEMBL
Affinity DataKi: 0.310nMAssay Description:Inhibition of electric eel AChE by LB plotMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Inhibition of Escherichia coli DHFRMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:In vitro inhibitory activity against beta-1 adrenergic receptor determined as pA2 in guinea pig atriaMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of wild type Staphylococcus aureus DHFRMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 7.80nMAssay Description:Inhibition of Escherichia coli DHFR assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 9.40nMAssay Description:In vitro inhibitory activity against beta-1 adrenergic receptor determined as pA2 in guinea pig atriaMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:In vitro inhibitory activity against beta-1 adrenergic receptor determined as pA2 in guinea pig atriaMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University
Curated by ChEMBL
Sun Yat-Sen University
Curated by ChEMBL
Affinity DataKi: 110nMAssay Description:Inhibition of electric eel AChE by LB plotMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University
Curated by ChEMBL
Sun Yat-Sen University
Curated by ChEMBL
Affinity DataKi: 3.86E+3nMAssay Description:Inhibition of electric eel AChE by LB plotMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University
Curated by ChEMBL
Sun Yat-Sen University
Curated by ChEMBL
Affinity DataKi: 1.46E+4nMAssay Description:Inhibition of electric eel AChE by LB plotMore data for this Ligand-Target Pair
Affinity DataKi: 3.15E+4nMAssay Description:Inhibition of Escherichia coli DHFR assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 3.59E+4nMAssay Description:Inhibition of Escherichia coli DHFR assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 0nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate incubated for 5 to 45 mins in presence of NADPH by LC/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.430nMAssay Description:Binding affinity against Dihydrofolate reductase of rat liverMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University
Curated by ChEMBL
Sun Yat-Sen University
Curated by ChEMBL
Affinity DataIC50: 0.480nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.670nMAssay Description:Antagonistic activity against beta-1 adrenergic receptor of isolated guinea pig atriaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.960nMAssay Description:Inhibition of Mycobacterium tuberculosis DHFRMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1nMAssay Description:In vitro inhibitory activity against beta-1 adrenergic receptor determined as pA2 in guinea pig atriaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human platelet Thromboxane synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Antagonistic activity against beta-1 adrenergic receptor of isolated guinea pig atriaMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:In vitro inhibition of dihydropteroate synthase from Escherichia coli.More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Antagonistic activity against beta-1 adrenergic receptor of isolated guinea pig atriaMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University
Curated by ChEMBL
Sun Yat-Sen University
Curated by ChEMBL
Affinity DataIC50: 2.62nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of wild type Staphylococcus aureus DHFRMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Antagonistic activity against beta-1 adrenergic receptor of isolated guinea pig atriaMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Binding affinity against Dihydrofolate reductase of rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Antagonistic activity against beta-1 adrenergic receptor of isolated guinea pig atriaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Binding affinity against Dihydrofolate reductase of rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Binding affinity against Dihydrofolate reductase of rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:In vitro inhibitory activity against beta-2 adrenergic receptor determined as pA2 in guinea pig tracheaMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Binding affinity against Dihydrofolate reductase of rat liverMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University
Curated by ChEMBL
Sun Yat-Sen University
Curated by ChEMBL
Affinity DataIC50: 4.81nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:In vitro inhibitory activity against beta-1 adrenergic receptor determined as pA2 in guinea pig atriaMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:In vitro inhibitory activity against beta-1 adrenergic receptor determined as pA2 in guinea pig atriaMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR using dihydrofolate as substrate preincubated for 1 min followed by substrate addition and ...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 6nMAssay Description:Inhibition of human platelet Thromboxane synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human platelet Thromboxane synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam and testosterone as substrate incubated for 5 to 45 mins in presence of NADPH by LC/MS...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of wild type Staphylococcus aureus DHFRMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of wild type Staphylococcus aureus DHFRMore data for this Ligand-Target Pair
Ligand InfoPDB
Affinity DataIC50: 20nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate incubated for 5 to 45 mins in presence of NADPH by LC/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of Mycobacterium tuberculosis DHFRMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 24nMAssay Description:Evaluated for norepinephrine as agonist.More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Binding affinity against Dihydrofolate reductase of rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Binding affinity against Dihydrofolate reductase of chicken liverMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:In vitro relative blocking action (pA2) of the post-synaptic Alpha-1 adrenergic receptor from rat and rabbit aortaMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Evaluated for norepinephrine as agonist.More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Antagonistic activity against beta-1 adrenergic receptor of isolated guinea pig atriaMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:In vitro inhibitory activity against beta-1 adrenergic receptor determined as pA2 in guinea pig atriaMore data for this Ligand-Target Pair