Affinity DataIC50: 0.100nMAssay Description:Inhibition of full length human recombinant HDAC6 incubated for 30 to 60 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant full length HDAC6 (unknown origin) using fluorophore conjugated substrate by microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.940nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.940nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals
Curated by ChEMBL
Elan Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of full length human recombinant HDAC6 using RHKKAc-AMC fluorogenic peptide as substrate incubated for 2 hrs by microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of HDAC6 (unknown origin) using FTS as substrate preincubated for 10 mins followed by substrate addition by microtiter plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using RHKKAc-AMC fluorogenic substrate by microtiter plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Elan Pharmaceuticals
Curated by ChEMBL
Elan Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant p38alpha after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of HDAC6 (unknown origin) using FTS as substrate preincubated for 10 mins followed by substrate addition by microtiter plate reader assayMore data for this Ligand-Target Pair
TargetS-adenosylmethionine synthase isoform type-2(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as S-adenosyl methionine production using L-methionine as substrate pretreated for 60 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Displacement of [3H]25-hydroxycholesterol from human RORc-LBD expressed in bacterial expression system after 3 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Displacement of [3H]25-hydroxycholesterol from human RORc-LBD expressed in bacterial expression system after 3 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 6.10nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 6.10nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 6.90nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]25-hydroxycholesterol from human RORc-LBD expressed in bacterial expression system after 3 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 7.70nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7.70nMAssay Description:Inhibition of full length human recombinant HDAC6 expressed in baculovirus infected Sf9 cells using RHKKAc fluorogenic peptide as substrate incubated...More data for this Ligand-Target Pair
Affinity DataIC50: 7.70nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
TargetS-adenosylmethionine synthase isoform type-2(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human MAT2A expressed in baculovirus infected Sf9 cells expression system assessed as S-adenosyl methionine production using L-methioni...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Displacement of [3H]25-hydroxycholesterol from human RORc-LBD expressed in bacterial expression system after 3 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 8.40nMAssay Description:Inhibition of recombinant full length HDAC1 (unknown origin) using fluorophore conjugated substrate by microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.20nMAssay Description:Displacement of [3H]25-hydroxycholesterol from human RORc-LBD expressed in bacterial expression system after 3 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Displacement of [3H]25-hydroxycholesterol from human RORc-LBD expressed in bacterial expression system after 3 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]25-hydroxycholesterol from human RORc-LBD expressed in bacterial expression system after 3 hrs by scintillation counting analysisMore data for this Ligand-Target Pair