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Found 114 with Last Name = 'rao' and Initial = 'z'
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM5025(Oseltamivir | US10919856, POSITIVE CONTROL | ethyl...)
Affinity DataIC50:  0.870nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai Institute of Materia Medica

LigandPNGBDBM420297(acs.jmedchem.1c00409_ST.30 | med.21724, Compound 6...)
Affinity DataIC50:  40nMAssay Description:Recombinant SARS-CoV-2 Mpro was expressed and purified from Escherichia coli (E. coli) (18, 25). A fluorescently labeled substrate, MCA-AVLQ SGFR-Lys...More data for this Ligand-Target Pair
Ligand InfoPurchasePDB
TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai Institute of Materia Medica

LigandPNGBDBM420296(Advanced SARS-CoV-2 Inhibitor 11a | MPI10 | acs.jm...)
Affinity DataIC50:  53nMAssay Description:Recombinant SARS-CoV-2 Mpro was expressed and purified from Escherichia coli (E. coli) (18, 25). A fluorescently labeled substrate, MCA-AVLQ SGFR-Lys...More data for this Ligand-Target Pair
Ligand InfoPurchasePDB
TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai Institute of Materia Medica

LigandPNGBDBM34233(2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...)
Affinity DataIC50:  670nMAssay Description:Recombinant SARS-CoV-2 Mpro with native N and C termini was expressed in Escherichia coli, and subsequently purified (Extended Data Fig. 1a, b). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai Institute of Materia Medica

LigandPNGBDBM50166940(NP-031112 | NP-12 | Tideglusib | US20230414581, Co...)
Affinity DataIC50:  1.55E+3nMAssay Description:Recombinant SARS-CoV-2 Mpro with native N and C termini was expressed in Escherichia coli, and subsequently purified (Extended Data Fig. 1a, b). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai Institute of Materia Medica

LigandPNGBDBM50431275(CARMOFUR | Carm-ofur | Mifurol | med.21724, Compou...)
Affinity DataIC50:  1.82E+3nMAssay Description:Recombinant SARS-CoV-2 Mpro with native N and C termini was expressed in Escherichia coli, and subsequently purified (Extended Data Fig. 1a, b). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai Institute of Materia Medica

LigandPNGBDBM50058655(1,1',1'',1'''-[disulfanediylbis(carbonothioylnitri...)
Affinity DataIC50:  9.35E+3nMAssay Description:Recombinant SARS-CoV-2 Mpro with native N and C termini was expressed in Escherichia coli, and subsequently purified (Extended Data Fig. 1a, b). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai Institute of Materia Medica

LigandPNGBDBM178090(5,8-dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl)nap...)
Affinity DataIC50:  1.58E+4nMAssay Description:Recombinant SARS-CoV-2 Mpro with native N and C termini was expressed in Escherichia coli, and subsequently purified (Extended Data Fig. 1a, b). The ...More data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497232(CHEMBL3290246)
Affinity DataIC50:  1.76E+4nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai Institute of Materia Medica

LigandPNGBDBM50426071(CHEMBL406050 | PX-12 | US9018255, PX-12 | med.2172...)
Affinity DataIC50:  2.14E+4nMAssay Description:Recombinant SARS-CoV-2 Mpro with native N and C termini was expressed in Escherichia coli, and subsequently purified (Extended Data Fig. 1a, b). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497231(CHEMBL3290243)
Affinity DataIC50:  2.85E+4nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497249(CHEMBL3290244)
Affinity DataIC50:  2.97E+4nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497240(CHEMBL3286435)
Affinity DataIC50:  3.67E+4nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497242(CHEMBL3290254)
Affinity DataIC50:  4.65E+4nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497230(CHEMBL3290242)
Affinity DataIC50:  5.75E+4nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497223(CHEMBL3290257)
Affinity DataIC50:  6.98E+4nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497221(CHEMBL3290252)
Affinity DataIC50:  7.13E+4nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497237(CHEMBL3290231)
Affinity DataIC50:  7.57E+4nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497248(CHEMBL3290229)
Affinity DataIC50:  8.69E+4nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497219(CHEMBL3290239)
Affinity DataIC50:  8.90E+4nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497234(CHEMBL3290251)
Affinity DataIC50:  8.96E+4nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497241(CHEMBL3290249)
Affinity DataIC50:  9.65E+4nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497236(CHEMBL3290256)
Affinity DataIC50:  1.06E+5nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497222(CHEMBL3290236)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497243(CHEMBL3290227)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497245(CHEMBL3290228)
Affinity DataIC50:  1.21E+5nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497238(CHEMBL3290237)
Affinity DataIC50:  1.25E+5nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai Institute of Materia Medica

LigandPNGBDBM419120(acs.jmedchem.1c00409_ST.487 | cmdc.202100576, 8d(N...)
Affinity DataIC50:  1.25E+5nMAssay Description:Recombinant SARS-CoV-2 Mpro with native N and C termini was expressed in Escherichia coli, and subsequently purified (Extended Data Fig. 1a, b). The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497217(CHEMBL3290225)
Affinity DataIC50:  1.29E+5nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497246(CHEMBL3290255)
Affinity DataIC50:  1.39E+5nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497226(CHEMBL3290234)
Affinity DataIC50:  1.45E+5nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497247(CHEMBL3290247)
Affinity DataIC50:  1.45E+5nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497220(CHEMBL3290245)
Affinity DataIC50:  1.65E+5nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497244(CHEMBL3290250)
Affinity DataIC50:  1.66E+5nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497225(CHEMBL3290232)
Affinity DataIC50:  1.89E+5nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497216(CHEMBL3290230)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497218(CHEMBL3290233)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497224(CHEMBL3290226)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497227(CHEMBL3290235)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497228(CHEMBL3290238)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497229(CHEMBL3290240)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497233(CHEMBL3290248)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497235(CHEMBL3290253)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Wuhan University School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50497239(CHEMBL3290241)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase after 1 hr by spectrofluorimetry using 2-(4-meythylumbelliferyl)-alpha-D-acetylneuramic acid as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM10759(2-acetoxyethyl(trimethyl)ammonium;bromide | 2-acet...)
Affinity DataEC50:  7nMAssay Description:Agonist activity at human muscarinic M2 receptor expressed in CHO cells after 30 mins by GTPgamma35S binding assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50038210(5-(2-Ethyl-2H-tetrazol-5-yl)-1-methyl-1,2,3,6-tetr...)
Affinity DataEC50:  296nMAssay Description:Agonist activity at human muscarinic M2 receptor expressed in CHO cells after 30 mins by GTPgamma35S binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50061705((R)-1-Aza-bicyclo[2.2.2]oct-3-yl-[(Z)-methoxyimino...)
Affinity DataEC50:  62nMAssay Description:Agonist activity at human muscarinic M2 receptor expressed in CHO cells after 30 mins by GTPgamma35S binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50119648(Talsaclidine)
Affinity DataEC50:  849nMAssay Description:Agonist activity at human muscarinic M2 receptor expressed in CHO cells after 30 mins by GTPgamma35S binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50003359(5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1-methyl-1,2...)
Affinity DataEC50:  121nMAssay Description:Agonist activity at human muscarinic M2 receptor expressed in CHO cells after 30 mins by GTPgamma35S binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM10759(2-acetoxyethyl(trimethyl)ammonium;bromide | 2-acet...)
Affinity DataEC50:  205nMAssay Description:Agonist activity at human muscarinic M3 receptor expressed in CHO cells after 30 mins by GTPgamma35S binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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