Affinity DataKi: 0.0000140nM ΔG°: -80.4kJ/molepH: 5.5 T: 2°CAssay Description:The method was a competitive displacement assay used to determine binding affinities of other inhibitors relative to that of GW0385. The inhibitor of...More data for this Ligand-Target Pair
Affinity DataKi: 0.0000480nM ΔG°: -77.3kJ/molepH: 5.5 T: 2°CAssay Description:The method was a competitive displacement assay used to determine binding affinities of other inhibitors relative to that of GW0385. The inhibitor of...More data for this Ligand-Target Pair
Affinity DataKi: 0.0000540nM ΔG°: -77.0kJ/molepH: 5.5 T: 2°CAssay Description:The method was a competitive displacement assay used to determine binding affinities of other inhibitors relative to that of GW0385. The inhibitor of...More data for this Ligand-Target Pair
Affinity DataKi: 0.0000580nM ΔG°: -76.8kJ/molepH: 5.5 T: 2°CAssay Description:The method was a competitive displacement assay used to determine binding affinities of other inhibitors relative to that of GW0385. The inhibitor of...More data for this Ligand-Target Pair
Affinity DataKi: 0.0000610nM ΔG°: -76.7kJ/molepH: 5.5 T: 2°CAssay Description:The method was a competitive displacement assay used to determine binding affinities of other inhibitors relative to that of GW0385. The inhibitor of...More data for this Ligand-Target Pair
Affinity DataKi: 0.000120nM ΔG°: -75.0kJ/molepH: 5.5 T: 2°CAssay Description:The method was a competitive displacement assay used to determine binding affinities of other inhibitors relative to that of GW0385. The inhibitor of...More data for this Ligand-Target Pair
Affinity DataKi: 0.000160nM ΔG°: -74.3kJ/molepH: 5.5 T: 2°CAssay Description:The method was a competitive displacement assay used to determine binding affinities of other inhibitors relative to that of GW0385. The inhibitor of...More data for this Ligand-Target Pair
Affinity DataKi: 0.000210nM ΔG°: -73.6kJ/molepH: 5.5 T: 2°CAssay Description:The method was a competitive displacement assay used to determine binding affinities of other inhibitors relative to that of GW0385. The inhibitor of...More data for this Ligand-Target Pair
Affinity DataKi: 0.000260nM ΔG°: -73.0kJ/molepH: 5.5 T: 2°CAssay Description:The method was a competitive displacement assay used to determine binding affinities of other inhibitors relative to that of GW0385. The inhibitor of...More data for this Ligand-Target Pair
Affinity DataKi: 0.000520nM ΔG°: -71.3kJ/molepH: 5.5 T: 2°CAssay Description:The method was a competitive displacement assay used to determine binding affinities of other inhibitors relative to that of GW0385. The inhibitor of...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]- spiperone radioligand binding at the dopamine binding site of rat caudateMore data for this Ligand-Target Pair
TargetCoagulation factor VII(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 0.620nMAssay Description:Inhibition of recombinant human coagulation factor 7AMore data for this Ligand-Target Pair
Affinity DataKi: 0.710nMAssay Description:Displacement of [3H]-NPA from rat brain Dopamine receptor D2More data for this Ligand-Target Pair
TargetCoagulation factor VII(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Inhibition of recombinant human coagulation factor 7AMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]- spiperone radioligand binding at the dopamine binding site of rat caudateMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]-NPA from rat brain Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]-NPA from rat brain Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Displacement of [3H]-NPA from rat brain Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Displacement of [3H]-NPA from rat brain Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Displacement of [3H]-NPA from rat brain Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]- QNB binding at the muscarinic-cholinergic binding site of rat brain S1More data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Displacement of [3H]-NPA from rat brain Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Displacement of [3H]-NPA from rat brain Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataKi: 4.80nMAssay Description:Displacement of [3H]-NPA from rat brain Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataKi: 5.10nMAssay Description:Displacement of [3H]-NPA from rat brain Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:Displacement of [3H]-NPA from rat brain Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataKi: 6.60nMAssay Description:Displacement of [3H]- apomorphine radioligand binding at the dopamine binding site of rat caudateMore data for this Ligand-Target Pair
Affinity DataKi: 6.80nMAssay Description:Displacement of [3H]- apomorphine radioligand binding at the dopamine binding site of rat caudateMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:In vitro inhibitory activity against procollagen C-terminal proteinase (PCP) in HT-1080 cells using synthetic peptide as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Displacement of [3H]- spiperone radioligand binding at the dopamine binding site of rat caudateMore data for this Ligand-Target Pair
Affinity DataKi: 7.20nMAssay Description:Displacement of [3H]- apomorphine radioligand binding at the dopamine binding site of rat caudateMore data for this Ligand-Target Pair
Affinity DataKi: 7.60nMAssay Description:Displacement of [3H]LSD radioligand binding at the serotonin-1 binding site of rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 7.80nMAssay Description:Displacement of [3H]LSD radioligand binding at the serotonin-1 binding site of rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:In vitro inhibitory activity against procollagen C-terminal proteinase (PCP) in HT-1080 cells using synthetic peptide as substrateMore data for this Ligand-Target Pair
TargetCoagulation factor VII(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 8.10nMAssay Description:Inhibition of recombinant human coagulation factor 7AMore data for this Ligand-Target Pair
Affinity DataKi: 8.20nMAssay Description:Displacement of [3H]LSD radioligand binding at the serotonin-1 binding site of rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 8.70nMAssay Description:Displacement of [3H]LSD radioligand binding at the serotonin-1 binding site of rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Ability to inhibit procollagen C-terminal proteinase (PCP) tested in vitroMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [3H]- spiperone radioligand binding at the dopamine binding site of rat caudateMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [3H]- apomorphine radioligand binding at the dopamine binding site of rat caudateMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [3H]- spiperone radioligand binding at the dopamine binding site of rat caudateMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [3H]LSD radioligand binding at the serotonin-1 binding site of rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [3H]- spiperone radioligand binding at the dopamine binding site of rat caudateMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Displacement of [3H]- prazosin radioligand binding at the alpha 1-adrenergic binding site of calf cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Displacement of [3H]LSD radioligand binding at the serotonin-1 binding site of rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:In vitro inhibitory activity against procollagen C-terminal proteinase (PCP) in HT-1080 cells using synthetic peptide as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Displacement of [3H]LSD radioligand binding at the serotonin-1 binding site of rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [3H]- QNB binding at the muscarinic-cholinergic binding site of rat brain S1More data for this Ligand-Target Pair