Affinity DataIC50: 3nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of BACE1 (unknown origin) using Biotin-GLTNIKTEEISEISYEVEFR-C[oregon green]KK-OH substrate assessed as fluorescence polarization by cell f...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of BACE1 (unknown origin) using Biotin-GLTNIKTEEISEISYEVEFR-C[oregon green]KK-OH substrate assessed as fluorescence polarization by cell f...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of BACE1 (unknown origin) using Biotin-GLTNIKTEEISEISYEVEFR-C[oregon green]KK-OH substrate assessed as fluorescence polarization by cell f...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of BACE1 (unknown origin) using Biotin-GLTNIKTEEISEISYEVEFR-C[oregon green]KK-OH substrate assessed as fluorescence polarization by cell f...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of BACE1 (unknown origin) using Biotin-GLTNIKTEEISEISYEVEFR-C[oregon green]KK-OH substrate assessed as fluorescence polarization by cell f...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of BACE1 (unknown origin) using Biotin-GLTNIKTEEISEISYEVEFR-C[oregon green]KK-OH substrate assessed as fluorescence polarization by cell f...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of BACE1 (unknown origin) using Biotin-GLTNIKTEEISEISYEVEFR-C[oregon green]KK-OH substrate assessed as fluorescence polarization by cell f...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of BACE1 (unknown origin) using Biotin-GLTNIKTEEISEISYEVEFR-C[oregon green]KK-OH substrate assessed as fluorescence polarization by cell f...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of BACE1 (unknown origin) using Biotin-GLTNIKTEEISEISYEVEFR-C[oregon green]KK-OH substrate assessed as fluorescence polarization by cell f...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of LPS-induced COX-2 in peritoneal macrophage of C57BL/J6 mouse assessed as prostaglandin E2 formation preincubated for 1 hr followed by L...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Shenogen Pharma Group
Curated by ChEMBL
Shenogen Pharma Group
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of wild type BRAF (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of BACE1 (unknown origin) using Biotin-GLTNIKTEEISEISYEVEFR-C[oregon green]KK-OH substrate assessed as fluorescence polarization by cell f...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against COX2 in feline whole blood assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
Affinity DataIC50: 33nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of BACE1 in human H4 cells overexpressing wild type human APP695 assessed as colorimetric reaction by Whole cell assayMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of COX2 by canine whole blood assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:In vitro inhibitory activity against cannine prostaglandin G/H synthase 1.More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: <50nMAssay Description:Inhibition of COX2 in canine whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: <50nMAssay Description:Inhibition of COX2 by canine whole blood assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Veterinary Medicine Research And Development Pfizer
Curated by ChEMBL
Affinity DataIC50: <50nMAssay Description:Inhibition of COX2 by canine whole blood assayMore data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of BACE1 in human H4 cells overexpressing wild type human APP695 assessed as colorimetric reaction by Whole cell assayMore data for this Ligand-Target Pair