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Found 345 with Last Name = 'sala' and Initial = 's'
TargetBile salt-activated lipase(Homo sapiens (Human))
University Of New Mexico

Curated by ChEMBL
LigandPNGBDBM50081700(6-Chloro-3-(2-cyclohexyl-ethyl)-pyran-2-one | CHEM...)
Affinity DataKi:  25nMAssay Description:Inhibition of the Pancreatic Cholesterol Esterase from porcineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt-activated lipase(Homo sapiens (Human))
University Of New Mexico

Curated by ChEMBL
LigandPNGBDBM50081696(6-Chloro-3-cyclopentyl-pyran-2-one | CHEMBL133091)
Affinity DataKi:  40nMAssay Description:Inhibition of the Pancreatic Cholesterol Esterase from porcineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt-activated lipase(Homo sapiens (Human))
University Of New Mexico

Curated by ChEMBL
LigandPNGBDBM50081698(6-Chloro-5-(2-cyclohexyl-ethyl)-pyran-2-one | CHEM...)
Affinity DataKi:  58nMAssay Description:Inhibition of the Pancreatic Cholesterol Esterase from porcineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt-activated lipase(Homo sapiens (Human))
University Of New Mexico

Curated by ChEMBL
LigandPNGBDBM50081697(6-Chloro-3-(3-cyclohexyl-propyl)-pyran-2-one | CHE...)
Affinity DataKi:  60nMAssay Description:Inhibition of the Pancreatic Cholesterol Esterase from porcineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50440737(CHEMBL2431120)
Affinity DataKi:  410nMAssay Description:Binding affinity to sigma-1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt-activated lipase(Homo sapiens (Human))
University Of New Mexico

Curated by ChEMBL
LigandPNGBDBM50081695(6-Chloro-3-(4-cyclohexyl-butyl)-pyran-2-one | CHEM...)
Affinity DataKi:  580nMAssay Description:Inhibition of the Pancreatic Cholesterol Esterase from porcineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50440737(CHEMBL2431120)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity to 5-HT3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50440737(CHEMBL2431120)
Affinity DataKi:  1.42E+3nMAssay Description:Binding affinity to histamine H1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt-activated lipase(Homo sapiens (Human))
University Of New Mexico

Curated by ChEMBL
LigandPNGBDBM50081694(6-Chloro-3-cyclohexylmethyl-pyran-2-one | CHEMBL44...)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of the Pancreatic Cholesterol Esterase from porcineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt-activated lipase(Homo sapiens (Human))
University Of New Mexico

Curated by ChEMBL
LigandPNGBDBM50081699(6-Chloro-3-cyclohexyl-pyran-2-one | CHEMBL134790)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of the Pancreatic Cholesterol Esterase from porcineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50440737(CHEMBL2431120)
Affinity DataKi:  2.54E+3nMAssay Description:Binding affinity to PBR receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGalactocerebrosidase(Mus musculus)
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50549785(CHEMBL4757193)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of mouse N-terminal His6-tagged GALC expressed in HEK293T cells using p-nitrophenyl-beta-D-galactopyranoside as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGalactocerebrosidase(Mus musculus)
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50549786(CHEMBL4741914)
Affinity DataKi:  2.30E+6nMAssay Description:Inhibition of mouse N-terminal His6-tagged GALC expressed in HEK293T cells using p-nitrophenyl-beta-D-galactopyranoside as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM50378304(CHEMBL568080)
Affinity DataIC50: <0.0300nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378288(CHEMBL567434)
Affinity DataIC50:  0.0300nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378319(CHEMBL568303)
Affinity DataIC50: <0.0400nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378305(CHEMBL583417)
Affinity DataIC50: <0.0400nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378289(CHEMBL565705)
Affinity DataIC50:  0.0400nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378290(CHEMBL568310)
Affinity DataIC50:  0.0400nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378291(CHEMBL568302)
Affinity DataIC50:  0.0400nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50003691(CHEMBL567624)
Affinity DataIC50: <0.0500nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50003691(CHEMBL567624)
Affinity DataIC50: <0.0500nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378292(CHEMBL566106)
Affinity DataIC50:  0.0500nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378293(CHEMBL566550)
Affinity DataIC50:  0.0600nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378294(CHEMBL566972)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50378292(CHEMBL566106)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50378290(CHEMBL568310)
Affinity DataIC50:  0.0800nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378295(CHEMBL565490)
Affinity DataIC50:  0.0800nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378296(CHEMBL568510)
Affinity DataIC50:  0.0900nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378297(CHEMBL566105)
Affinity DataIC50:  0.0900nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378298(CHEMBL583421)
Affinity DataIC50:  0.0900nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378299(CHEMBL568079)
Affinity DataIC50:  0.0900nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50378288(CHEMBL567434)
Affinity DataIC50:  0.0900nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378212(CHEMBL575450)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378300(CHEMBL565930)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50378297(CHEMBL566105)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50378289(CHEMBL565705)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378301(CHEMBL568311)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378302(CHEMBL583615)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378303(CHEMBL567208)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50378304(CHEMBL568080)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50378305(CHEMBL583417)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50378306(CHEMBL567647)
Affinity DataIC50:  0.140nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50378293(CHEMBL566550)
Affinity DataIC50:  0.140nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50378298(CHEMBL583421)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378307(CHEMBL566329)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50378300(CHEMBL565930)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378308(CHEMBL568509)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50378309(CHEMBL568093)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378309(CHEMBL568093)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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