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Found 819 with Last Name = 'samajdar' and Initial = 's'
TargetCyclin-dependent kinase 13(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478951(2-(6-(1-acryloyl-2,5-dihydro-1H-pyrrol-3-yl)pyridi...)
Affinity DataIC50:  0.900nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity mitogen-activated protein kinase kinase 1 [K97R](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM200424(US10011599, Example 51 | US9227969, 51 | US9629836...)
Affinity DataIC50:  1nMAssay Description:The radioactive filter binding assay is standardized using recombinant human activated BRAF (V599E) kinase (Cat No. 14-557) and kinase dead MEK1 (K97...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM200424(US10011599, Example 51 | US9227969, 51 | US9629836...)
Affinity DataIC50:  1nMpH: 7.5Assay Description:A BRAF-MEK-ERK cascade assay is used to evaluate the effects of these compounds as inhibitors of the MAP kinase pathway. An enzymatic cascade assay i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM200424(US10011599, Example 51 | US9227969, 51 | US9629836...)
Affinity DataIC50:  1nMAssay Description:[MEK1 1mM ATP IC50 uM] A BRAF-MEK-ERK cascade assay is used to evaluate the effects of these compounds as inhibitors of the MAP kinase pathway. An en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM200427(US10011599, Example 54 | US9227969, 54 | US9629836...)
Affinity DataIC50:  1.5nMpH: 7.5Assay Description:A BRAF-MEK-ERK cascade assay is used to evaluate the effects of these compounds as inhibitors of the MAP kinase pathway. An enzymatic cascade assay i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity mitogen-activated protein kinase kinase 1 [K97R](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM200427(US10011599, Example 54 | US9227969, 54 | US9629836...)
Affinity DataIC50:  1.5nMAssay Description:The radioactive filter binding assay is standardized using recombinant human activated BRAF (V599E) kinase (Cat No. 14-557) and kinase dead MEK1 (K97...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM200427(US10011599, Example 54 | US9227969, 54 | US9629836...)
Affinity DataIC50:  1.5nMAssay Description:[MEK1 1mM ATP IC50 uM] A BRAF-MEK-ERK cascade assay is used to evaluate the effects of these compounds as inhibitors of the MAP kinase pathway. An en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity mitogen-activated protein kinase kinase 1 [K97R](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM200420(US10011599, Example 47 | US9227969, 47 | US9629836...)
Affinity DataIC50:  1.70nMAssay Description:The radioactive filter binding assay is standardized using recombinant human activated BRAF (V599E) kinase (Cat No. 14-557) and kinase dead MEK1 (K97...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM200420(US10011599, Example 47 | US9227969, 47 | US9629836...)
Affinity DataIC50:  1.70nMpH: 7.5Assay Description:A BRAF-MEK-ERK cascade assay is used to evaluate the effects of these compounds as inhibitors of the MAP kinase pathway. An enzymatic cascade assay i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM200420(US10011599, Example 47 | US9227969, 47 | US9629836...)
Affinity DataIC50:  1.70nMAssay Description:[MEK1 1mM ATP IC50 uM] A BRAF-MEK-ERK cascade assay is used to evaluate the effects of these compounds as inhibitors of the MAP kinase pathway. An en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM402212(1-(4-(8-(2-chloro-4-((6-(hydroxymethyl)pyridin-2- ...)
Affinity DataIC50:  2nMAssay Description:[MEK1 1mM ATP IC50 uM] A BRAF-MEK-ERK cascade assay is used to evaluate the effects of these compounds as inhibitors of the MAP kinase pathway. An en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity mitogen-activated protein kinase kinase 1 [K97R](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM200417(US9227969, 44 | US9629836, 44)
Affinity DataIC50:  2nMAssay Description:The radioactive filter binding assay is standardized using recombinant human activated BRAF (V599E) kinase (Cat No. 14-557) and kinase dead MEK1 (K97...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM200417(US9227969, 44 | US9629836, 44)
Affinity DataIC50:  2nMpH: 7.5Assay Description:A BRAF-MEK-ERK cascade assay is used to evaluate the effects of these compounds as inhibitors of the MAP kinase pathway. An enzymatic cascade assay i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50547958(CHEMBL4789918)
Affinity DataIC50:  2nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM200436(US10011599, Example 65 | US9227969, 65 | US9629836...)
Affinity DataIC50:  2.40nMAssay Description:[MEK1 1mM ATP IC50 uM] A BRAF-MEK-ERK cascade assay is used to evaluate the effects of these compounds as inhibitors of the MAP kinase pathway. An en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM200436(US10011599, Example 65 | US9227969, 65 | US9629836...)
Affinity DataIC50:  2.40nMpH: 7.5Assay Description:A BRAF-MEK-ERK cascade assay is used to evaluate the effects of these compounds as inhibitors of the MAP kinase pathway. An enzymatic cascade assay i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity mitogen-activated protein kinase kinase 1 [K97R](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM200436(US10011599, Example 65 | US9227969, 65 | US9629836...)
Affinity DataIC50:  2.40nMAssay Description:The radioactive filter binding assay is standardized using recombinant human activated BRAF (V599E) kinase (Cat No. 14-557) and kinase dead MEK1 (K97...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity mitogen-activated protein kinase kinase 1 [K97R](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM200461(US10011599, Example 90 | US9227969, 90 | US9629836...)
Affinity DataIC50:  2.60nMAssay Description:The radioactive filter binding assay is standardized using recombinant human activated BRAF (V599E) kinase (Cat No. 14-557) and kinase dead MEK1 (K97...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity mitogen-activated protein kinase kinase 1 [K97R](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM200460(US10011599, Example 89 | US9227969, 89 | US9629836...)
Affinity DataIC50:  2.60nMAssay Description:The radioactive filter binding assay is standardized using recombinant human activated BRAF (V599E) kinase (Cat No. 14-557) and kinase dead MEK1 (K97...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM200461(US10011599, Example 90 | US9227969, 90 | US9629836...)
Affinity DataIC50:  2.60nMAssay Description:[MEK1 1mM ATP IC50 uM] A BRAF-MEK-ERK cascade assay is used to evaluate the effects of these compounds as inhibitors of the MAP kinase pathway. An en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM200460(US10011599, Example 89 | US9227969, 89 | US9629836...)
Affinity DataIC50:  2.60nMAssay Description:[MEK1 1mM ATP IC50 uM] A BRAF-MEK-ERK cascade assay is used to evaluate the effects of these compounds as inhibitors of the MAP kinase pathway. An en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM200460(US10011599, Example 89 | US9227969, 89 | US9629836...)
Affinity DataIC50:  2.60nMpH: 7.5Assay Description:A BRAF-MEK-ERK cascade assay is used to evaluate the effects of these compounds as inhibitors of the MAP kinase pathway. An enzymatic cascade assay i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM200461(US10011599, Example 90 | US9227969, 90 | US9629836...)
Affinity DataIC50:  2.60nMpH: 7.5Assay Description:A BRAF-MEK-ERK cascade assay is used to evaluate the effects of these compounds as inhibitors of the MAP kinase pathway. An enzymatic cascade assay i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity mitogen-activated protein kinase kinase 1 [K97R](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM200409(US10011599, Example 37 | US9227969, 37 | US9629836...)
Affinity DataIC50:  2.70nMAssay Description:The radioactive filter binding assay is standardized using recombinant human activated BRAF (V599E) kinase (Cat No. 14-557) and kinase dead MEK1 (K97...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity mitogen-activated protein kinase kinase 1 [K97R](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM200465(US10011599, Example 94 | US9227969, 94 | US9629836...)
Affinity DataIC50:  2.70nMAssay Description:The radioactive filter binding assay is standardized using recombinant human activated BRAF (V599E) kinase (Cat No. 14-557) and kinase dead MEK1 (K97...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM200465(US10011599, Example 94 | US9227969, 94 | US9629836...)
Affinity DataIC50:  2.70nMAssay Description:[MEK1 1mM ATP IC50 uM] A BRAF-MEK-ERK cascade assay is used to evaluate the effects of these compounds as inhibitors of the MAP kinase pathway. An en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM200409(US10011599, Example 37 | US9227969, 37 | US9629836...)
Affinity DataIC50:  2.70nMpH: 7.5Assay Description:A BRAF-MEK-ERK cascade assay is used to evaluate the effects of these compounds as inhibitors of the MAP kinase pathway. An enzymatic cascade assay i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50547947(CHEMBL4760206)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM200465(US10011599, Example 94 | US9227969, 94 | US9629836...)
Affinity DataIC50:  2.70nMpH: 7.5Assay Description:A BRAF-MEK-ERK cascade assay is used to evaluate the effects of these compounds as inhibitors of the MAP kinase pathway. An enzymatic cascade assay i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM200409(US10011599, Example 37 | US9227969, 37 | US9629836...)
Affinity DataIC50:  2.70nMAssay Description:[MEK1 1mM ATP IC50 uM] A BRAF-MEK-ERK cascade assay is used to evaluate the effects of these compounds as inhibitors of the MAP kinase pathway. An en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50547949(CHEMBL4743091)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM200430(US9227969, 58)
Affinity DataIC50:  3nMpH: 7.5Assay Description:A BRAF-MEK-ERK cascade assay is used to evaluate the effects of these compounds as inhibitors of the MAP kinase pathway. An enzymatic cascade assay i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity mitogen-activated protein kinase kinase 1 [K97R](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM200403(US10011599, Example 31 | US9227969, 31 | US9629836...)
Affinity DataIC50:  3nMAssay Description:The radioactive filter binding assay is standardized using recombinant human activated BRAF (V599E) kinase (Cat No. 14-557) and kinase dead MEK1 (K97...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM200403(US10011599, Example 31 | US9227969, 31 | US9629836...)
Affinity DataIC50:  3nMpH: 7.5Assay Description:A BRAF-MEK-ERK cascade assay is used to evaluate the effects of these compounds as inhibitors of the MAP kinase pathway. An enzymatic cascade assay i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 13(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478952((E)-2-(1'-(but-2-enoyl)-1',2',5',6'-tetrahydro-[2,...)
Affinity DataIC50:  3nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM323134(US10011599, Example 58 | US9629836, 58)
Affinity DataIC50:  3nMAssay Description:[MEK1 1mM ATP IC50 uM] A BRAF-MEK-ERK cascade assay is used to evaluate the effects of these compounds as inhibitors of the MAP kinase pathway. An en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 13(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478281(2-(1'-acryloyl-1',2',3',6'-tetrahydro-[2,4'-bipyri...)
Affinity DataIC50:  3nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 13(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478782((Isomer-1 of compound-35): 2-(1''-acryloyl-1'',2''...)
Affinity DataIC50:  3nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity mitogen-activated protein kinase kinase 1 [K97R](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM323134(US10011599, Example 58 | US9629836, 58)
Affinity DataIC50:  3nMAssay Description:The radioactive filter binding assay is standardized using recombinant human activated BRAF (V599E) kinase (Cat No. 14-557) and kinase dead MEK1 (K97...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM200403(US10011599, Example 31 | US9227969, 31 | US9629836...)
Affinity DataIC50:  3nMAssay Description:[MEK1 1mM ATP IC50 uM] A BRAF-MEK-ERK cascade assay is used to evaluate the effects of these compounds as inhibitors of the MAP kinase pathway. An en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50547959(CHEMBL4750630)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM200444(US10011599, Example 73 | US9227969, 73 | US9629836...)
Affinity DataIC50:  3.60nMAssay Description:[MEK1 1mM ATP IC50 uM] A BRAF-MEK-ERK cascade assay is used to evaluate the effects of these compounds as inhibitors of the MAP kinase pathway. An en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50547962(CHEMBL4784665)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50547955(CHEMBL4796558)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM200444(US10011599, Example 73 | US9227969, 73 | US9629836...)
Affinity DataIC50:  3.60nMpH: 7.5Assay Description:A BRAF-MEK-ERK cascade assay is used to evaluate the effects of these compounds as inhibitors of the MAP kinase pathway. An enzymatic cascade assay i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity mitogen-activated protein kinase kinase 1 [K97R](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM200444(US10011599, Example 73 | US9227969, 73 | US9629836...)
Affinity DataIC50:  3.60nMAssay Description:The radioactive filter binding assay is standardized using recombinant human activated BRAF (V599E) kinase (Cat No. 14-557) and kinase dead MEK1 (K97...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM323138(US10011599, Example 62 | US9629836, 62)
Affinity DataIC50:  3.70nMAssay Description:[MEK1 1mM ATP IC50 uM] A BRAF-MEK-ERK cascade assay is used to evaluate the effects of these compounds as inhibitors of the MAP kinase pathway. An en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM200400(US10011599, Example 28 | US9227969, 28 | US9629836...)
Affinity DataIC50:  3.70nMAssay Description:[MEK1 1mM ATP IC50 uM] A BRAF-MEK-ERK cascade assay is used to evaluate the effects of these compounds as inhibitors of the MAP kinase pathway. An en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity mitogen-activated protein kinase kinase 1 [K97R](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM323138(US10011599, Example 62 | US9629836, 62)
Affinity DataIC50:  3.70nMAssay Description:The radioactive filter binding assay is standardized using recombinant human activated BRAF (V599E) kinase (Cat No. 14-557) and kinase dead MEK1 (K97...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM200400(US10011599, Example 28 | US9227969, 28 | US9629836...)
Affinity DataIC50:  3.70nMpH: 7.5Assay Description:A BRAF-MEK-ERK cascade assay is used to evaluate the effects of these compounds as inhibitors of the MAP kinase pathway. An enzymatic cascade assay i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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