TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Southern Research
Curated by ChEMBL
Southern Research
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...More data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of NNMT in human U2OS cells assessed as reduction in MNA production after 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Southern Research
Curated by ChEMBL
Southern Research
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...More data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataIC50: 512nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataIC50: 588nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataIC50: 922nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of NNMT in mouse 3T3L1 cells assessed as reduction in MNA production after 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataIC50: 2.37E+3nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Southern Research
Curated by ChEMBL
Southern Research
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Southern Research
Curated by ChEMBL
Southern Research
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...More data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of mouse NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Southern Research
Curated by ChEMBL
Southern Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Council of Scientific and Industrial Research (Csir) Indian Institute of Chemical Biology
Council of Scientific and Industrial Research (Csir) Indian Institute of Chemical Biology
Affinity DataIC50: 6.40E+3nMAssay Description:The tautomerase activity of MIFs was monitored by following the tautomerization of L-dopachrome methyl ester by the recombinant MIFs in the presence ...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Council of Scientific and Industrial Research (Csir) Indian Institute of Chemical Biology
Council of Scientific and Industrial Research (Csir) Indian Institute of Chemical Biology
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of human cloned MIF tautomerase activity expressed in Escherichia coli assessed as conversion of L-dopachrome methyl ester to indolecarbox...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Council of Scientific and Industrial Research (Csir) Indian Institute of Chemical Biology
Council of Scientific and Industrial Research (Csir) Indian Institute of Chemical Biology
Affinity DataIC50: 9.50E+3nMAssay Description:The tautomerase activity of MIFs was monitored by following the tautomerization of L-dopachrome methyl ester by the recombinant MIFs in the presence ...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor-like protein(Plasmodium yoelii)
Council of Scientific and Industrial Research (Csir) Indian Institute of Chemical Biology
Council of Scientific and Industrial Research (Csir) Indian Institute of Chemical Biology
Affinity DataIC50: 9.80E+3nMAssay Description:The tautomerase activity of MIFs was monitored by following the tautomerization of L-dopachrome methyl ester by the recombinant MIFs in the presence ...More data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Council of Scientific and Industrial Research (Csir) Indian Institute of Chemical Biology
Council of Scientific and Industrial Research (Csir) Indian Institute of Chemical Biology
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of human cloned MIF tautomerase activity expressed in Escherichia coli assessed as conversion of L-dopachrome methyl ester to indolecarbox...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Council of Scientific and Industrial Research (Csir) Indian Institute of Chemical Biology
Council of Scientific and Industrial Research (Csir) Indian Institute of Chemical Biology
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of human cloned MIF tautomerase activity expressed in Escherichia coli assessed as conversion of L-dopachrome methyl ester to indolecarbox...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Council of Scientific and Industrial Research (Csir) Indian Institute of Chemical Biology
Council of Scientific and Industrial Research (Csir) Indian Institute of Chemical Biology
Affinity DataIC50: 1.52E+4nMAssay Description:Inhibition of human cloned MIF tautomerase activity expressed in Escherichia coli assessed as conversion of L-dopachrome methyl ester to indolecarbox...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Council of Scientific and Industrial Research (Csir) Indian Institute of Chemical Biology
Council of Scientific and Industrial Research (Csir) Indian Institute of Chemical Biology
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of human cloned MIF tautomerase activity expressed in Escherichia coli assessed as conversion of L-dopachrome methyl ester to indolecarbox...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Council of Scientific and Industrial Research (Csir) Indian Institute of Chemical Biology
Council of Scientific and Industrial Research (Csir) Indian Institute of Chemical Biology
Affinity DataIC50: 1.75E+4nMAssay Description:The tautomerase activity of MIFs was monitored by following the tautomerization of L-dopachrome methyl ester by the recombinant MIFs in the presence ...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Council of Scientific and Industrial Research (Csir) Indian Institute of Chemical Biology
Council of Scientific and Industrial Research (Csir) Indian Institute of Chemical Biology
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of human cloned MIF tautomerase activity expressed in Escherichia coli assessed as conversion of L-dopachrome methyl ester to indolecarbox...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor-like protein(Plasmodium yoelii)
Council of Scientific and Industrial Research (Csir) Indian Institute of Chemical Biology
Council of Scientific and Industrial Research (Csir) Indian Institute of Chemical Biology
Affinity DataIC50: 2.24E+4nMAssay Description:The tautomerase activity of MIFs was monitored by following the tautomerization of L-dopachrome methyl ester by the recombinant MIFs in the presence ...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Plasmodium falciparum)
Council of Scientific and Industrial Research (Csir) Indian Institute of Chemical Biology
Council of Scientific and Industrial Research (Csir) Indian Institute of Chemical Biology
Affinity DataIC50: 2.25E+4nMAssay Description:The tautomerase activity of MIFs was monitored by following the tautomerization of L-dopachrome methyl ester by the recombinant MIFs in the presence ...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Southern Research
Curated by ChEMBL
Southern Research
Curated by ChEMBL
Affinity DataIC50: 2.41E+4nMAssay Description:Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Council of Scientific and Industrial Research (Csir) Indian Institute of Chemical Biology
Council of Scientific and Industrial Research (Csir) Indian Institute of Chemical Biology
Affinity DataIC50: 2.52E+4nMAssay Description:Inhibition of human cloned MIF tautomerase activity expressed in Escherichia coli assessed as conversion of L-dopachrome methyl ester to indolecarbox...More data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Southern Research
Curated by ChEMBL
Southern Research
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...More data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Southern Research
Curated by ChEMBL
Southern Research
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Southern Research
Curated by ChEMBL
Southern Research
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Southern Research
Curated by ChEMBL
Southern Research
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...More data for this Ligand-Target Pair