TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human recombinant HDAC8 using H2N-Arg-His-Lys(Ac)-Lys(Ac)-AMC as substrate after 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human HDAC6 using RHKKAc fluorogenic peptide substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human HDAC6 using Z-(Ac)Lys-AMC as substrate after 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 6.90nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 cells using Z-(Ac)Lys-AMC as substrate ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant HDAC8 using H2N-Arg-His-Lys(Ac)-Lys(Ac)-AMC as substrate after 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 cells using Z-(Ac)Lys-AMC as substrate ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human HDAC6 using Z-(Ac)Lys-AMC as substrate after 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human HDAC6 using RHKKAc fluorogenic peptide substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human HDAC6 using ZMAL as substrate incubated for 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human HDAC6 using ZMAL as substrate incubated for 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 cells using Z-(Ac)Lys-AMC as substrate ...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of human HDAC8 (1 to 377 residues) expressed in Escherichia coli BL21(DE3) using Boc-Lys(TFA)-AMC as substrate preincubated for 5 mins fol...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of human recombinant HDAC8 using H2N-Arg-His-Lys(Ac)-Lys(Ac)-AMC as substrate after 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human HDAC1 using Z-(Ac)Lys-AMC as substrate after 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 cells using Z-(Ac)Lys-AMC as substrate ...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human HDAC6 using ZMAL as substrate incubated for 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant HDAC8 using H2N-Arg-His-Lys(Ac)-Lys(Ac)-AMC as substrate after 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of human His-thioredoxin-tagged HDAC8 expressed in Escherichia coli BL21 (DE3) cells using Fluor de Lys (R)-HDAC8 as substrate by fluorome...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 cells using Z-(Ac)Lys-AMC as substrate ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 cells using Z-(Ac)Lys-AMC as substrate ...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant HDAC8 using H2N-Arg-His-Lys(Ac)-Lys(Ac)-AMC as substrate after 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus infected Sf9 insect cells using Z(Ac)Lys-AMC as substrate by flu...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich
Curated by ChEMBL
Ludwig-Maximilians University Munich
Curated by ChEMBL
Affinity DataIC50: 62nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 cells using Z-(Ac)Lys-AMC as substrate ...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 64nMAssay Description:Inhibition of human His-thioredoxin-tagged HDAC8 expressed in Escherichia coli BL21 (DE3) cells using Fluor de Lys (R)-HDAC8 as substrate by fluorome...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of human recombinant HDAC8 using H2N-Arg-His-Lys(Ac)-Lys(Ac)-AMC as substrate after 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair