Compile Data Set for Download or QSAR
maximum 50k data
Found 277 with Last Name = 'shirasaki' and Initial = 'y'
TargetPeptide deformylase, mitochondrial(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50089194((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-2-hydroxymethyl-...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity of the compound towards Peptide deformylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPeptide deformylase, mitochondrial(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50089194((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-2-hydroxymethyl-...)
Affinity DataIC50:  1.5nMAssay Description:In vitro inhibitory concentration required against peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159725(US9035059, 19-4)
Affinity DataIC50:  2nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159724(US9035059, 19-3)
Affinity DataIC50:  4nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159734(US9035059, 23-1 | US9035059, 24-1/24-2)
Affinity DataIC50:  4nMT: 2°CAssay Description:An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159732(US9035059, 20-4)
Affinity DataIC50:  5nMT: 2°CAssay Description:An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159705(US9035059, 18-7)
Affinity DataIC50:  7nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159711(US9035059, 18-16)
Affinity DataIC50:  10nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159740(US9035059, 24-11 | US9035059, 24-5/24-6)
Affinity DataIC50:  10nMT: 2°CAssay Description:An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159734(US9035059, 23-1 | US9035059, 24-1/24-2)
Affinity DataIC50:  13nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159736(US9035059, 23-3)
Affinity DataIC50:  13nMT: 2°CAssay Description:An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM242568(US9422240, 1-378)
Affinity DataIC50:  14nMpH: 7.5Assay Description:The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159730(US9035059, 20-2)
Affinity DataIC50:  14nMT: 2°CAssay Description:An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159735(US9035059, 23-2)
Affinity DataIC50:  14nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM242554(US9422240, 1-296)
Affinity DataIC50:  15nMpH: 7.5Assay Description:The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM242567(US9422240, 1-377)
Affinity DataIC50:  15nMpH: 7.5Assay Description:The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159657(US9035059, 7-76)
Affinity DataIC50:  16nMT: 2°CAssay Description:An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM242526(US9422240, 1-4)
Affinity DataIC50:  19nMpH: 7.5Assay Description:The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM242563(US9422240, 1-366)
Affinity DataIC50:  19nMpH: 7.5Assay Description:The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50189833((S)-N-butyl-3-((S)-2-(4-fluorophenylsulfonamido)-3...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human erythrocyte mu calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM242577(US9422240, 1-443)
Affinity DataIC50:  21nMpH: 7.5Assay Description:The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCalpain-2 catalytic subunit(Sus scrofa)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50189833((S)-N-butyl-3-((S)-2-(4-fluorophenylsulfonamido)-3...)
Affinity DataIC50:  21nMAssay Description:Inhibition of porcein kidney m calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM242566(US9422240, 1-376)
Affinity DataIC50:  22nMpH: 7.5Assay Description:The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50114340((S)-2-(4-Fluoro-benzenesulfonylamino)-N-((S)-1-for...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human erythrocyte mu calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159729(US9035059, 19-12)
Affinity DataIC50:  23nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159701(US9035059, 17-5)
Affinity DataIC50:  24nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM242542(US9422240, 1-265 | US9422240, 1-355)
Affinity DataIC50:  24nMpH: 7.5Assay Description:The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159636(US9035059, 6-75)
Affinity DataIC50:  24nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM242535(US9422240, 1-254)
Affinity DataIC50:  24nMpH: 7.5Assay Description:The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159682(US9035059, 10-5/10-6)
Affinity DataIC50:  25nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM242575(US9422240, 1-409)
Affinity DataIC50:  25nMpH: 7.5Assay Description:The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159708(US9035059, 18-12)
Affinity DataIC50:  26nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159624(US9035059, 6-33)
Affinity DataIC50:  26nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159681(US9035059, 10-3/10-4)
Affinity DataIC50:  26nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM242571(US9422240, 1-392)
Affinity DataIC50:  26nMpH: 7.5Assay Description:The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM242564(US9422240, 1-367)
Affinity DataIC50:  26nMpH: 7.5Assay Description:The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159615(US9035059, 6-17)
Affinity DataIC50:  28nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159727(US9035059, 19-8)
Affinity DataIC50:  28nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159707(US9035059, 18-11)
Affinity DataIC50:  29nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159666(US9035059, 8-5)
Affinity DataIC50:  29nMT: 2°CAssay Description:An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159734(US9035059, 23-1 | US9035059, 24-1/24-2)
Affinity DataIC50:  29nMT: 2°CAssay Description:An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159723(US9035059, 19-2)
Affinity DataIC50:  30nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159622(US9035059, 6-31)
Affinity DataIC50:  31nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159683(US9035059, 10-7/10-8)
Affinity DataIC50:  31nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159623(US9035059, 6-32)
Affinity DataIC50:  31nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM242572(US9422240, 1-393)
Affinity DataIC50:  32nMpH: 7.5Assay Description:The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159718(US9035059, 18-25)
Affinity DataIC50:  33nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159741(US9035059, 24-7/24-8)
Affinity DataIC50:  34nMT: 2°CAssay Description:An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159616(US9035059, 6-18)
Affinity DataIC50:  35nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159667(US9035059, 8-6)
Affinity DataIC50:  35nMT: 2°CAssay Description:An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...More data for this Ligand-Target Pair
In DepthDetails US Patent
Displayed 1 to 50 (of 277 total ) | Next | Last >>
Jump to: