Affinity DataIC50: 0.320nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 0.760nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 1.22nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 1.33nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 1.62nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 1.82nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 2.19nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 2.42nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 2.82nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 3.48nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 3.98nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 4.21nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 6.51nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 6.53nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 6.72nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 7.24nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 7.83nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 8.17nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 8.64nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
Affinity DataIC50: 12.3nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Affinity DataIC50: 13.7nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hamdard University
Curated by ChEMBL
Hamdard University
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of HRG stimulated erbB2 phosphorylation in human MCF-7 cells preincubated for 90 mins followed by HRG addition for 5 mins by ELISA methodMore data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
Affinity DataIC50: 98nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
Affinity DataIC50: 98nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hamdard University
Curated by ChEMBL
Hamdard University
Curated by ChEMBL
Affinity DataIC50: 610nMAssay Description:Inhibition of HRG stimulated erbB2 phosphorylation in human MCF-7 cells preincubated for 90 mins followed by HRG addition for 5 mins by ELISA methodMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hamdard University
Curated by ChEMBL
Hamdard University
Curated by ChEMBL
Affinity DataIC50: 910nMAssay Description:Inhibition of HRG stimulated erbB2 phosphorylation in human MCF-7 cells preincubated for 90 mins followed by HRG addition for 5 mins by ELISA methodMore data for this Ligand-Target Pair
Affinity DataIC50: 979nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
Affinity DataIC50: 980nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hamdard University
Curated by ChEMBL
Hamdard University
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of HRG stimulated erbB2 phosphorylation in human MCF-7 cells preincubated for 90 mins followed by HRG addition for 5 mins by ELISA methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hamdard University
Curated by ChEMBL
Hamdard University
Curated by ChEMBL
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of HRG stimulated erbB2 phosphorylation in human MCF-7 cells preincubated for 90 mins followed by HRG addition for 5 mins by ELISA methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hamdard University
Curated by ChEMBL
Hamdard University
Curated by ChEMBL
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of HRG stimulated erbB2 phosphorylation in human MCF-7 cells preincubated for 90 mins followed by HRG addition for 5 mins by ELISA methodMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hamdard University
Curated by ChEMBL
Hamdard University
Curated by ChEMBL
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of HRG stimulated erbB2 phosphorylation in human MCF-7 cells preincubated for 90 mins followed by HRG addition for 5 mins by ELISA methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
Affinity DataIC50: 3.18E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
Affinity DataIC50: 3.18E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
Affinity DataIC50: 3.32E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
Affinity DataIC50: 3.32E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hamdard University
Curated by ChEMBL
Hamdard University
Curated by ChEMBL
Affinity DataIC50: 3.69E+4nMAssay Description:Inhibition of HRG stimulated erbB2 phosphorylation in human MCF-7 cells preincubated for 90 mins followed by HRG addition for 5 mins by ELISA methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.97E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
Affinity DataIC50: 3.97E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair