Affinity DataKi: 0.0600nMAssay Description:Tested for inhibition of HIV protease using fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Tested for inhibition of HIV protease using fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Tested for inhibition of HIV protease using fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using 125[I]-PYY as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.340nMAssay Description:In vitro binding affinity of the compound was determined against human type 1a growth hormone secretagogue receptor (hGHS-R1a), using [125I]-ghrelin ...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Lublin
Curated by ChEMBL
Medical University Of Lublin
Curated by ChEMBL
Affinity DataKi: 0.340nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Medical University Of Lublin
Curated by ChEMBL
Medical University Of Lublin
Curated by ChEMBL
Affinity DataKi: 0.370nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in HEK293 cell membranes measured after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Tested for inhibition of HIV protease using fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:In vitro binding affinity of the compound was determined against human type 1a growth hormone secretagogue receptor (hGHS-R1a), using [125I]-ghrelin ...More data for this Ligand-Target Pair
Affinity DataKi: 0.720nMAssay Description:Displacement of [3H]spiperone from human dopamine D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Eberhard Karls University T£Bingen
Curated by ChEMBL
Eberhard Karls University T£Bingen
Curated by ChEMBL
Affinity DataKi: 0.830nMAssay Description:Inhibition of recombinant human full length N-terminal GST-fused MPS1 (1 to 857 residues) using histone H3 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.840nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using 125[I]-PYY as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.960nMAssay Description:Displacement of [3H]spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]-Histamine from human histamine 4 receptor transfected in HEK293T cells incubated for 16 hrs by liquid scintillation counter anal...More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Tested for inhibition of HIV protease using fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Binding affinity of the compound to the human Neuropeptide Y receptor type 5 was determined using [125I]- [PYY] as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Tested for inhibition of HIV protease using fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using 125[I]-PYY as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radiogigand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Binding affinity of the compound to the rat Neuropeptide Y receptor type 5 was determined using [125I]- [Leu31,Pro34]PYY as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Lublin
Curated by ChEMBL
Medical University Of Lublin
Curated by ChEMBL
Affinity DataKi: 1.91nMAssay Description:Antagonist activity at 5HT1AMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Tested for inhibition of HIV protease using fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]-Histamine from human histamine 3 receptor transfected in HEK293T cells incubated for 16 hrs by liquid scintillation counter anal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Lublin
Curated by ChEMBL
Medical University Of Lublin
Curated by ChEMBL
Affinity DataKi: 2.51nMAssay Description:Antagonist activity at 5HT1AMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using 125[I]-PYY as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Lublin
Curated by ChEMBL
Medical University Of Lublin
Curated by ChEMBL
Affinity DataKi: 2.69nMAssay Description:Antagonist activity at 5HT1AMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Tested for inhibition of HIV protease using fluorogenic substrateMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Lublin
Curated by ChEMBL
Medical University Of Lublin
Curated by ChEMBL
Affinity DataKi: 3.02nMAssay Description:Antagonist activity at 5HT1AMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]Spiperone from human D2S receptor expressed in CHOK1 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in CHO cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using 125[I]-PYY as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radiogigand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]-Histamine from human histamine 3 receptor transfected in HEK293T cells incubated for 16 hrs by liquid scintillation counter anal...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radiogigand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataKi: 4.40nMAssay Description:Inhibition of human DYRK1A incubated for 90 mins in presence of ATP by Z-LYTE based FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.70nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using 125[I]-PYY as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 4.90nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radiogigand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:In vitro binding affinity of the compound was determined against human type 1a growth hormone secretagogue receptor (hGHS-R1a), using [125I]-ghrelin ...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Lublin
Curated by ChEMBL
Medical University Of Lublin
Curated by ChEMBL
Affinity DataKi: 5.01nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Universidad De Santiago De Compostela
Curated by ChEMBL
Universidad De Santiago De Compostela
Curated by ChEMBL
Affinity DataKi: 5.16nMAssay Description:Displacement of [3H]spiperone from human D3 receptor expressed in CHO-K1 cells by radioligand competitive binding analysisMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Universidad De Santiago De Compostela
Curated by ChEMBL
Universidad De Santiago De Compostela
Curated by ChEMBL
Affinity DataKi: 5.20nMAssay Description:Displacement of [3H]spiperone from human D3 receptor expressed in CHO-K1 cells by radioligand competitive binding analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in CHO cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in CHO cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Lublin
Curated by ChEMBL
Medical University Of Lublin
Curated by ChEMBL
Affinity DataKi: 6.03nMAssay Description:Antagonist activity at 5HT1AMore data for this Ligand-Target Pair
Affinity DataKi: 6.20nMAssay Description:Displacement of [3H]spiperone from human D2S receptor expressed in CHO-K1 cells by radioligand competitive binding analysisMore data for this Ligand-Target Pair
Affinity DataKi: 6.20nMAssay Description:Displacement of [3H]spiperone from human D2S receptor expressed in CHO-K1 cells by radioligand competitive binding analysisMore data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:Displacement of [3H]-Histamine from human histamine 3 receptor transfected in HEK293T cells incubated for 16 hrs by liquid scintillation counter anal...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Lublin
Curated by ChEMBL
Medical University Of Lublin
Curated by ChEMBL
Affinity DataKi: 6.46nMAssay Description:Antagonist activity at 5HT1AMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Lublin
Curated by ChEMBL
Medical University Of Lublin
Curated by ChEMBL
Affinity DataKi: 6.46nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Universidad De Santiago De Compostela
Curated by ChEMBL
Universidad De Santiago De Compostela
Curated by ChEMBL
Affinity DataKi: 6.80nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair