Affinity DataKi: 0.450nMAssay Description:Binding affinity to Homo sapiens (human) H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Binding affinity to Homo sapiens (human) H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Binding affinity to Rattus norvegicus (rat) H3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.360nMAssay Description:Inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid by HPLC analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Reversible inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Reversible inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid after 30 mins by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Reversible inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid after 60 mins by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Reversible inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid after 90 mins by HPLC analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid by HPLC analysisMore data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of human ABHD6 containing pCMV6-AC-hABHD6 transfected into HEK293 cellsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Reversible inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 93nMAssay Description:Reversible inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid after 30 mins by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 98nMAssay Description:Inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 155nMAssay Description:Reversible inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid after 60 mins by HPLC analysisMore data for this Ligand-Target Pair
TargetLysophosphatidylserine lipase ABHD12(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of human ABHD12 containing pCMV6-XL4-hABHD12 transfected into HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 208nMAssay Description:Inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 209nMAssay Description:Reversible inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 224nMAssay Description:Reversible inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid after 30 mins by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 257nMAssay Description:Reversible inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid after 60 mins by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 309nMAssay Description:Reversible inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid after 90 mins by HPLC analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 645nMAssay Description:Inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 676nMAssay Description:Reversible inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid after 90 mins by HPLC analysisMore data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:Inhibition of human ABHD6 containing pCMV6-AC-hABHD6 transfected into HEK293 cellsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of human ABHD6 containing pCMV6-AC-hABHD6 transfected into HEK293 cellsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 2.57E+3nMAssay Description:Inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid by HPLC analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human FAAH using [ethanolamine 1-3H] substrate assessed as radioactivity by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 6.91E+3nMAssay Description:Inhibition of human FAAH using [ethanolamine 1-3H] substrate assessed as radioactivity by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 7.24E+3nMAssay Description:Inhibition of human FAAH using [ethanolamine 1-3H] substrate assessed as radioactivity by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair