TargetHistone deacetylase 1(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of HDAC10 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 64nMAssay Description:Inhibition of HDAC10 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 118nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 119nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 319nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 5(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 354nMAssay Description:Inhibition of HDAC5 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Radioligand displacement assay for the binding of [125I]-Glu-Pro-Gln-pTyr-Glu-Glu-Ile-Pro-Ile-Tyr-Leu to SRC SH2 domainMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of [35S]-labeled SH2-GST Abl binding to the phospho-PDGF receptor intracellular domainMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of [35S]-labeled SH2-GST Abl binding to the phospho-PDGF receptor intracellular domainMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Radioligand displacement assay for the binding of [125I]-Glu-Pro-Gln-pTyr-Glu-Glu-Ile-Pro-Ile-Tyr-Leu to SRC SH2 domainMore data for this Ligand-Target Pair
TargetHistone deacetylase 9(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 927nMAssay Description:Inhibition of HDAC9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of [35S]-labeled SH2-GST Abl binding to the phospho-PDGF receptor intracellular domainMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of [35S]-labeled SH2-GST Src binding to phospho-PDGF receptor intracellular domainMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Radioligand displacement assay for the binding of [125I]-Glu-Pro-Gln-pTyr-Glu-Glu-Ile-Pro-Ile-Tyr-Leu to ABL SH2 domainMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of [35S]-labeled SH2-GST Src binding to phospho-PDGF receptor intracellular domainMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of [35S]-labeled SH2-GST Abl binding to the phospho-PDGF receptor intracellular domainMore data for this Ligand-Target Pair
TargetHistone deacetylase 7(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of HDAC7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Radioligand displacement assay for the binding of [125I]-Glu-Pro-Gln-pTyr-Glu-Glu-Ile-Pro-Ile-Tyr-Leu to ABL SH2 domainMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Radioligand displacement assay for the binding of [125I]-Glu-Pro-Gln-pTyr-Glu-Glu-Ile-Pro-Ile-Tyr-Leu to ABL SH2 domainMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Radioligand displacement assay for the binding of [125I]-Glu-Pro-Gln-pTyr-Glu-Glu-Ile-Pro-Ile-Tyr-Leu to SRC SH2 domainMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Radioligand displacement assay for the binding of [125I]-Glu-Pro-Gln-pTyr-Glu-Glu-Ile-Pro-Ile-Tyr-Leu to ABL SH2 domainMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Functional antagonism against ETA receptor in rat aortic rings expressed as pA2 valueMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of [35S]-labeled SH2-GST Abl binding to the phospho-PDGF receptor intracellular domainMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+3nMAssay Description:Radioligand displacement assay for the binding of [125I]-Glu-Pro-Gln-pTyr-Glu-Glu-Ile-Pro-Ile-Tyr-Leu to SRC SH2 domainMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of [35S]-labeled SH2-GST Abl binding to the phospho-PDGF receptor intracellular domainMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Radioligand displacement assay for the binding of [125I]-Glu-Pro-Gln-pTyr-Glu-Glu-Ile-Pro-Ile-Tyr-Leu to ABL SH2 domainMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+3nMAssay Description:Radioligand displacement assay for the binding of [125I]-Glu-Pro-Gln-pTyr-Glu-Glu-Ile-Pro-Ile-Tyr-Leu to SRC SH2 domainMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+3nMAssay Description:Radioligand displacement assay for the binding of [125I]-Glu-Pro-Gln-pTyr-Glu-Glu-Ile-Pro-Ile-Tyr-Leu to ABL SH2 domainMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of [35S]-labeled SH2-GST Src binding to phospho-PDGF receptor intracellular domainMore data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of [35S]-labeled SH2-GST Src binding to phospho-PDGF receptor intracellular domainMore data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of [35S]-labeled SH2-GST Abl binding to the phospho-PDGF receptor intracellular domainMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of [35S]-labeled SH2-GST Src binding to phospho-PDGF receptor intracellular domainMore data for this Ligand-Target Pair
Affinity DataIC50: 6.10E+3nMAssay Description:Radioligand displacement assay for the binding of [125I]-Glu-Pro-Gln-pTyr-Glu-Glu-Ile-Pro-Ile-Tyr-Leu to SRC SH2 domainMore data for this Ligand-Target Pair
Affinity DataIC50: 6.70E+3nMAssay Description:Radioligand displacement assay for the binding of [125I]-Glu-Pro-Gln-pTyr-Glu-Glu-Ile-Pro-Ile-Tyr-Leu to SRC SH2 domainMore data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of [35S]-labeled SH2-GST Abl binding to the phospho-PDGF receptor intracellular domainMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Radioligand displacement assay for the binding of [125I]-Glu-Pro-Gln-pTyr-Glu-Glu-Ile-Pro-Ile-Tyr-Leu to SRC SH2 domainMore data for this Ligand-Target Pair
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of [35S]-labeled SH2-GST Src binding to phospho-PDGF receptor intracellular domainMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90E+3nMAssay Description:Radioligand displacement assay for the binding of [125I]-Glu-Pro-Gln-pTyr-Glu-Glu-Ile-Pro-Ile-Tyr-Leu to SRC SH2 domainMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of [35S]-labeled SH2-GST Src binding to phospho-PDGF receptor intracellular domainMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Orchid Chemicals & Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 9.30E+3nMAssay Description:Radioligand displacement assay for the binding of [125I]-Glu-Pro-Gln-pTyr-Glu-Glu-Ile-Pro-Ile-Tyr-Leu to SRC SH2 domainMore data for this Ligand-Target Pair
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of [35S]-labeled SH2-GST Src binding to phospho-PDGF receptor intracellular domainMore data for this Ligand-Target Pair
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of [35S]-labeled SH2-GST Abl binding to the phospho-PDGF receptor intracellular domainMore data for this Ligand-Target Pair