Affinity DataIC50: 0.380nMAssay Description:Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Inhibition of His-tagged HDAC6 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Inhibition of His-tagged HDAC6 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:Inhibition of His-tagged HDAC6 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.60nMAssay Description:Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 8.5nMAssay Description:Inhibition of His-tagged HDAC1 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Displacement of biotinylated acetylated histone H4 peptide from human recombinant N-terminal GST-tagged BRD4 BD1 (49 to 170 residues) expressed in Es...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of His-tagged HDAC6 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMAssay Description:Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 11.1nMAssay Description:Inhibition of His-tagged HDAC10 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
TargetProtein c-Fos/Transcription factor Jun(Homo sapiens (Human))
Signal Pharmaceuticals
Curated by ChEMBL
Signal Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Concentration required to inhibit activator protein-1(AP-1) mediated transcriptional activation in human Jurkat T-cellsMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Southern Research
Curated by ChEMBL
Southern Research
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...More data for this Ligand-Target Pair
Affinity DataIC50: 26.7nMAssay Description:Inhibition of His-tagged HDAC1 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 28.3nMAssay Description:Inhibition of His-tagged HDAC10 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 34.5nMAssay Description:Inhibition of His-tagged HDAC6 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 36.9nMAssay Description:Inhibition of His-tagged HDAC1 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40.9nMAssay Description:Inhibition of His-tagged HDAC1 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Displacement of biotinylated acetylated histone H4 peptide from human recombinant N-terminal GST-tagged BRD4 BD1 (49 to 170 residues) expressed in Es...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 42.1nMAssay Description:Inhibition of His-tagged HDAC10 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 45.5nMAssay Description:Inhibition of His-tagged HDAC6 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 46.1nMAssay Description:Inhibition of His-tagged HDAC10 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Signal Pharmaceuticals
Curated by ChEMBL
Signal Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:In vitro inhibitory activity against human Jurkat T-Cells stably transfected with an Nuclear factor kappa B transcription factorMore data for this Ligand-Target Pair
TargetCyclic AMP-dependent transcription factor ATF-1(Homo sapiens (Human))
Signal Pharmaceuticals
Curated by ChEMBL
Signal Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Concentration required to inhibit activator protein-1(AP-1) mediated transcriptional activation in human Jurkat T-cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 95.3nMAssay Description:Inhibition of His-tagged HDAC6 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
TargetProtein c-Fos/Transcription factor Jun(Homo sapiens (Human))
Signal Pharmaceuticals
Curated by ChEMBL
Signal Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cellsMore data for this Ligand-Target Pair
TargetProtein c-Fos/Transcription factor Jun(Homo sapiens (Human))
Signal Pharmaceuticals
Curated by ChEMBL
Signal Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Concentration required to inhibit activator protein-1(AP-1) mediated transcriptional activation in human Jurkat T-cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 102nMAssay Description:Inhibition of His-tagged HDAC6 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 113nMAssay Description:Inhibition of His-tagged HDAC2 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 114nMAssay Description:Inhibition of His-tagged HDAC6 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
TargetCyclic AMP-dependent transcription factor ATF-1(Homo sapiens (Human))
Signal Pharmaceuticals
Curated by ChEMBL
Signal Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of His-tagged HDAC1 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
TargetCyclic AMP-dependent transcription factor ATF-1(Homo sapiens (Human))
Signal Pharmaceuticals
Curated by ChEMBL
Signal Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1More data for this Ligand-Target Pair
Affinity DataIC50: 152nMAssay Description:Inhibition of His-tagged HDAC1 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 156nMAssay Description:Inhibition of His-tagged HDAC2 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 167nMAssay Description:Inhibition of His-tagged HDAC2 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Signal Pharmaceuticals
Curated by ChEMBL
Signal Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:In vitro inhibitory activity against human Jurkat T-Cells stably transfected with an Nuclear factor kappa B transcription factorMore data for this Ligand-Target Pair