TargetCysteine protease ATG4B(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Institute Of Molecular Physiology
Curated by ChEMBL
Institute Of Molecular Physiology
Curated by ChEMBL
TargetCysteine protease ATG4B(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of ATG4B (unknown origin) using ProLC3B as substrate by LC/MS analysisMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Institute Of Molecular Physiology
Curated by ChEMBL
Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Institute Of Molecular Physiology
Curated by ChEMBL
Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of BTKMore data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant ATG4B (unknown origin) expressed in Escherichia coli BL21(DE3) using LC3-PLA2 as substrate by fluoroscence based assayMore data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Affinity DataIC50: 3.24E+3nMAssay Description:Inhibition of ATG4B (unknown origin) using FRET-GABARAPL2 as substrate preincubated for 30 mins followed by substrate addition and measured after 30 ...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Institute Of Molecular Physiology
Curated by ChEMBL
Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CDK2/Cyclin BMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Institute Of Molecular Physiology
Curated by ChEMBL
Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CDK2/Cyclin EMore data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of ATG4B (unknown origin) using N-(His)6-LC3B(L123C)Biotin as substrate preincubated for 30 mins and measured after 1 hr by AlphaScreen me...More data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of ATG4B (unknown origin) using N-(His)6-LC3B(L123C) as substrate preincubated for 1 hr followed by substrate addition and measured after ...More data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Affinity DataIC50: 2.45E+4nMAssay Description:Inhibition of ATG4B (unknown origin) using pim-FG-PABA-AMC as substrate preincubated for 30 mins followed by substrate addition and measured every 15...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Institute Of Molecular Physiology
Curated by ChEMBL
Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of ERK1/MAPKMore data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of ATG4B (unknown origin) using N-(His)6-LC3B(L123C)Biotin as substrate preincubated for 30 mins and measured after 1 hr by AlphaScreen me...More data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Affinity DataIC50: 3.13E+4nMAssay Description:Inhibition of ATG4B (unknown origin) using N-(His)6-LC3B(L123C) as substrate preincubated for 1 hr followed by substrate addition and measured after ...More data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of ATG4B (unknown origin) using N-(His)6-LC3B(L123C) as substrate preincubated for 1 hr followed by substrate addition and measured after ...More data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of ATG4B (unknown origin) using GST-labelled LC3B as substrate after 24 hrs followed by substrate addition and measured after 3 mins by co...More data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of ATG4B (unknown origin) using N-(His)6-LC3B(L123C) as substrate preincubated for 1 hr followed by substrate addition and measured after ...More data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of ATG4B (unknown origin) using N-(His)6-LC3B(L123C) as substrate preincubated for 1 hr followed by substrate addition and measured after ...More data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Affinity DataIC50: 6.80E+4nMAssay Description:Inhibition of ATG4B (unknown origin) using N-(His)6-LC3B(L123C)Biotin as substrate preincubated for 30 mins and measured after 1 hr by AlphaScreen me...More data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Affinity DataIC50: 6.90E+4nMAssay Description:Inhibition of ATG4B (unknown origin) using N-(His)6-LC3B(L123C)Biotin as substrate preincubated for 30 mins and measured after 1 hr by AlphaScreen me...More data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Affinity DataIC50: 7.90E+4nMAssay Description:Inhibition of ATG4B (unknown origin) using N-(His)6-LC3B(L123C) as substrate preincubated for 1 hr followed by substrate addition and measured after ...More data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of ATG4B (unknown origin) using N-(His)6-LC3B(L123C) as substrate preincubated for 1 hr followed by substrate addition and measured after ...More data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Affinity DataIC50: 9.70E+4nMAssay Description:Inhibition of ATG4B (unknown origin) using N-(His)6-LC3B(L123C) as substrate preincubated for 1 hr followed by substrate addition and measured after ...More data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Affinity DataIC50: 1.04E+5nMAssay Description:Inhibition of ATG4B (unknown origin) using N-(His)6-LC3B(L123C)Biotin as substrate preincubated for 30 mins and measured after 1 hr by AlphaScreen me...More data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Affinity DataIC50: 1.11E+5nMAssay Description:Inhibition of ATG4B (unknown origin) using N-(His)6-LC3B(L123C)Biotin as substrate preincubated for 30 mins and measured after 1 hr by AlphaScreen me...More data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Affinity DataIC50: 1.13E+5nMAssay Description:Inhibition of ATG4B (unknown origin) using N-(His)6-LC3B(L123C)Biotin as substrate preincubated for 30 mins and measured after 1 hr by AlphaScreen me...More data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Affinity DataIC50: 1.19E+5nMAssay Description:Inhibition of ATG4B (unknown origin) using N-(His)6-LC3B(L123C)Biotin as substrate preincubated for 30 mins and measured after 1 hr by AlphaScreen me...More data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Affinity DataIC50: 1.32E+5nMAssay Description:Inhibition of ATG4B (unknown origin) using N-(His)6-LC3B(L123C)Biotin as substrate preincubated for 30 mins and measured after 1 hr by AlphaScreen me...More data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of ATG4B (unknown origin) using N-(His)6-LC3B(L123C) as substrate preincubated for 1 hr followed by substrate addition and measured after ...More data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Affinity DataIC50: 2.15E+5nMAssay Description:Inhibition of ATG4B (unknown origin) using N-(His)6-LC3B(L123C) as substrate preincubated for 1 hr followed by substrate addition and measured after ...More data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Affinity DataIC50: 2.35E+5nMAssay Description:Inhibition of ATG4B (unknown origin) using N-(His)6-LC3B(L123C)Biotin as substrate preincubated for 30 mins and measured after 1 hr by AlphaScreen me...More data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Affinity DataIC50: 2.80E+5nMAssay Description:Inhibition of ATG4B (unknown origin) using N-(His)6-LC3B(L123C) as substrate preincubated for 1 hr followed by substrate addition and measured after ...More data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of ATG4B (unknown origin) using N-(His)6-LC3B(L123C)Biotin as substrate preincubated for 30 mins and measured after 1 hr by AlphaScreen me...More data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of ATG4B (unknown origin) using N-(His)6-LC3B(L123C)Biotin as substrate preincubated for 30 mins and measured after 1 hr by AlphaScreen me...More data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Institute Of Advanced Chemistry Of Catalonia
Curated by ChEMBL
Affinity DataIC50: 3.15E+5nMAssay Description:Inhibition of ATG4B (unknown origin) using N-(His)6-LC3B(L123C)Biotin as substrate preincubated for 30 mins and measured after 1 hr by AlphaScreen me...More data for this Ligand-Target Pair
Affinity DataIC50: 6.40E+5nMAssay Description:Inhibition of IRKMore data for this Ligand-Target Pair
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataKd: 7nMAssay Description:Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataKd: 17nMAssay Description:Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataKd: 82nMAssay Description:Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataKd: 108nMAssay Description:Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataKd: 1.25E+3nMAssay Description:Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataKd: 35nMAssay Description:Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataKd: 16nMAssay Description:Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataKd: 36nMAssay Description:Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataKd: 26nMAssay Description:Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataKd: 251nMAssay Description:Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataKd: 347nMAssay Description:Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataKd: 689nMAssay Description:Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assayMore data for this Ligand-Target Pair