Compile Data Set for Download or QSAR
maximum 50k data
Found 75 with Last Name = 'valentine' and Initial = 'jj'
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216194(CHEMBL391935 | N-(2-chlorophenethyl)-N-(pyrrolidin...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127711(CHEMBL3629719)
Affinity DataIC50:  16nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127710(CHEMBL3629720)
Affinity DataIC50:  26nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216201(CHEMBL233987 | N-(2-methoxyphenethyl)-4-(6-aza-bic...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216180(CHEMBL233799 | N-(2-methoxyphenethyl)-N-(pyrrolidi...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127718(CHEMBL3629713)
Affinity DataIC50:  65nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216199(4-(2-aza-bicyclo[2.2.1]heptan-2-ylmethyl)-N-(2-met...)
Affinity DataIC50:  95nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216188(CHEMBL233422 | N-(2-methoxyphenethyl)-4-(((1S,2S)-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127711(CHEMBL3629719)
Affinity DataIC50:  110nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216193(CHEMBL233609 | N-(2-methoxyphenethyl)-4-(((S)-2-(m...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127712(CHEMBL3629718)
Affinity DataIC50:  140nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216197(CHEMBL233610 | N-(2-methoxyphenethyl)-4-(((S)-2-(m...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216181((R)-N-(2-methoxyphenethyl)-4-((diethylamino)methyl...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127710(CHEMBL3629720)
Affinity DataIC50:  200nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127720(CHEMBL3629711)
Affinity DataIC50:  220nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127716(CHEMBL3629715)
Affinity DataIC50:  240nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216204(CHEMBL394028 | N-(2-methoxyphenethyl)-4-(piperidin...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127718(CHEMBL3629713)
Affinity DataIC50:  260nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127723(CHEMBL3629708)
Affinity DataIC50:  310nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216206(CHEMBL393989 | N-(2-methoxyphenethyl)-4-(benzyloxy...)
Affinity DataIC50:  310nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127722(CHEMBL3629709)
Affinity DataIC50:  310nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216191(CHEMBL232587 | N-(2,6-dichlorophenethyl)-4-((dieth...)
Affinity DataIC50:  430nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127750(CHEMBL3629705)
Affinity DataIC50:  450nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127752(CHEMBL3629703)
Affinity DataIC50:  510nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216187(CHEMBL232777 | N-(3-chlorophenethyl)-4-(benzyloxy)...)
Affinity DataIC50:  510nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216196(CHEMBL231776 | N-(2-methoxyphenethyl)-4-((diethyla...)
Affinity DataIC50:  540nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216183(CHEMBL233573 | N-(2-chlorophenethyl)-4-(benzyloxy)...)
Affinity DataIC50:  590nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127750(CHEMBL3629705)
Affinity DataIC50:  800nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127720(CHEMBL3629711)
Affinity DataIC50:  800nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127751(CHEMBL3629704)
Affinity DataIC50:  810nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216207(CHEMBL233572 | N-(2-chlorophenethyl)-4-((diethylam...)
Affinity DataIC50:  840nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127722(CHEMBL3629709)
Affinity DataIC50:  880nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127716(CHEMBL3629715)
Affinity DataIC50:  900nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216208((S)-N-(2-methoxyphenethyl)-4-((diethylamino)methyl...)
Affinity DataIC50:  970nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127753(CHEMBL3629702)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127752(CHEMBL3629703)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127712(CHEMBL3629718)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50434377(CHEMBL2387002)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of PDGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127723(CHEMBL3629708)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216186(CHEMBL232577 | N-(2-chlorophenethyl)-4-isopropoxy-...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50280413(5'-bromo-1'-(3,4-dichlorobenzyl)spiro[tetrahydro-1...)
Affinity DataIC50:  1.50E+3nMAssay Description:Compound was evaluated for displacement of radiolabelled [I-125]GRP from rat brain receptor; 1.5-3 microMMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGastrin-releasing peptide receptor(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50280412(2-{3-[1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-meth-...)
Affinity DataIC50:  1.50E+3nMAssay Description:Compound was evaluated for displacement of radiolabelled [I-125]GRP from rat brain receptor; 1.5-3 microMMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127721(CHEMBL3629710)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216203(4-diethylaminomethyl-N-pyrrolidin-3-yl-N-(2-o-toly...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127719(CHEMBL3629712)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127713(CHEMBL3629717)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127753(CHEMBL3629702)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127751(CHEMBL3629704)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216190(CHEMBL232776 | N-(4-chlorophenethyl)-4-((diethylam...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127719(CHEMBL3629712)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 75 total ) | Next | Last >>
Jump to: