Affinity DataIC50: 0.0200nMAssay Description:Antagonist activity at human AR in MDA-MB453-MMTV-luci cells by functional assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Antagonist activity at human AR in MDA-MB453-MMTV-luci cells by functional assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1nMAssay Description:Antagonist activity at human AR in MDA-MB453-MMTV-luci cells by functional assayMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9.80nMAssay Description:Displacement of [3H]-DHT from human recombinant AR expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10.9nMAssay Description:Displacement of [3H]-DHT from human recombinant AR expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 11.9nMAssay Description:Antagonist activity at human AR in MDA-MB453-MMTV-luci cells by functional assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14.7nMAssay Description:Displacement of [3H]-DHT from human recombinant AR expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMpH: 7.4 T: 2°CAssay Description:The competitive radio-ligand binding analysis was performed on human AR extracts from transfected Sf9 cells in the presence or absence of differing c...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMpH: 7.4 T: 2°CAssay Description:The competitive radio-ligand binding analysis was performed on human AR extracts from transfected Sf9 cells in the presence or absence of differing c...More data for this Ligand-Target Pair
Affinity DataIC50: 20.1nMAssay Description:Antagonist activity at human AR in MDA-MB453-MMTV-luci cells by functional assayMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMpH: 7.4 T: 2°CAssay Description:The competitive radio-ligand binding analysis was performed on human AR extracts from transfected Sf9 cells in the presence or absence of differing c...More data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Displacement of [3H]-DHT from human recombinant AR expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMpH: 7.4 T: 2°CAssay Description:The competitive radio-ligand binding analysis was performed on human AR extracts from transfected Sf9 cells in the presence or absence of differing c...More data for this Ligand-Target Pair
Affinity DataIC50: 37nMpH: 7.4 T: 2°CAssay Description:The competitive radio-ligand binding analysis was performed on human AR extracts from transfected Sf9 cells in the presence or absence of differing c...More data for this Ligand-Target Pair
Affinity DataIC50: 39.9nMAssay Description:Displacement of [3H]-DHT from human recombinant AR expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 39.9nMpH: 7.4 T: 2°CAssay Description:The competitive radio-ligand binding analysis was performed on human AR extracts from transfected Sf9 cells in the presence or absence of differing c...More data for this Ligand-Target Pair
Affinity DataIC50: 56.7nMAssay Description:Displacement of [3H]-DHT from human recombinant AR expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMpH: 7.4 T: 2°CAssay Description:The competitive radio-ligand binding analysis was performed on human AR extracts from transfected Sf9 cells in the presence or absence of differing c...More data for this Ligand-Target Pair
Affinity DataIC50: 61.2nMAssay Description:Displacement of [3H]-DHT from human recombinant AR expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 95nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Antagonist activity at human AR in MDA-MB453-MMTV-luci cells by functional assayMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 146nMAssay Description:Displacement of [3H]-DHT from human recombinant AR expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Displacement of [3H]-DHT from human recombinant AR expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 229nMAssay Description:Displacement of [3H]-DHT from human recombinant AR expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 399nMAssay Description:Antagonist activity at human AR in MDA-MB453-MMTV-luci cells by functional assayMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 510nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 540nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 590nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 840nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 843nMAssay Description:Antagonist activity at human AR in MDA-MB453-MMTV-luci cells by functional assayMore data for this Ligand-Target Pair
Affinity DataIC50: 955nMAssay Description:Displacement of [3H]-DHT from human recombinant AR expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 970nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 989nMAssay Description:Displacement of [3H]-DHT from human recombinant AR expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human AR in MDA-MB453-MMTV-luci cells by functional assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.31E+3nMAssay Description:Displacement of [3H]-DHT from human recombinant AR expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.54E+3nMAssay Description:Displacement of [3H]-DHT from human recombinant AR expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMpH: 7.4 T: 2°CAssay Description:The competitive radio-ligand binding analysis was performed on human AR extracts from transfected Sf9 cells in the presence or absence of differing c...More data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Displacement of [3H]-DHT from human recombinant AR expressed in Sf9 cellsMore data for this Ligand-Target Pair