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Found 403 with Last Name = 'wang' and Initial = 'jw'
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  1nMAssay Description:Inhibition of rat brain AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50313194(1,3alpha,8-trimethyl-1,2,3,3alpha,8,8alpha-hexahyd...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of rat brain AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50413835(CHEMBL5282046)
Affinity DataIC50:  5nMAssay Description:Displacement of [3H]UR-MK299 from human neuropeptide Y Y1 receptor in human SK-N-MC cells measured after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50415761(CHEMBL5285102)
Affinity DataIC50:  5nMAssay Description:Displacement of [3H]UR-MK299 from human neuropeptide Y Y2 receptor expressed in CHO cells measured after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50014107((-)-(4-Methoxy-phenyl)-carbamic acid 1,3a,8-trimet...)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of rat plasma BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50414478(CHEMBL5285941)
Affinity DataIC50:  6nMAssay Description:Displacement of [3H]UR-MK299 from human neuropeptide Y Y1 receptor in human SK-N-MC cells measured after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50313190(1,3alpha,8-trimethyl-1,2,3,3alpha,8,8alpha-hexahyd...)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of rat brain AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50414272(CHEMBL5278608)
Affinity DataIC50:  7nMAssay Description:Displacement of [3H]UR-MK299 from human neuropeptide Y Y1 receptor in human SK-N-MC cells measured after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50414481(CHEMBL5280302)
Affinity DataIC50:  7nMAssay Description:Displacement of [3H]UR-MK299 from human neuropeptide Y Y1 receptor in human SK-N-MC cells measured after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50415765(CHEMBL5280977)
Affinity DataIC50:  7nMAssay Description:Displacement of [3H]UR-MK299 from human neuropeptide Y Y2 receptor expressed in CHO cells measured after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50313191(1,3alpha,8-trimethyl-1,2,3,3alpha,8,8alpha-hexahyd...)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of rat brain AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of rat plasma BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50414477(CHEMBL5291188)
Affinity DataIC50:  8nMAssay Description:Displacement of [3H]UR-MK299 from human neuropeptide Y Y1 receptor in human SK-N-MC cells measured after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50584365(CHEMBL5078327)
Affinity DataIC50:  8nMAssay Description:Displacement of BODIPY from APC-labelled RORgammat LBD (unknown origin) incubated for 1 hrs by binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50412732(CHEMBL5272275)
Affinity DataIC50:  8nMAssay Description:Displacement of [3H]UR-KK200 from human neuropeptide Y Y4 receptor expressed in CHO-mtAEQ cells co-expressing Gqi5 measured after 90 mins by scintill...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50414482(CHEMBL5282428)
Affinity DataIC50:  8nMAssay Description:Displacement of [3H]UR-MK299 from human neuropeptide Y Y1 receptor in human SK-N-MC cells measured after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50313191(1,3alpha,8-trimethyl-1,2,3,3alpha,8,8alpha-hexahyd...)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of rat plasma BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50313195(1,3alpha,8-trimethyl-1,2,3,3alpha,8,8alpha-hexahyd...)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of rat brain AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50415762(CHEMBL5283401)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]UR-MK299 from human neuropeptide Y Y2 receptor expressed in CHO cells measured after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50461084(CHEMBL4225088)
Affinity DataIC50:  10nMAssay Description:Displacement of BODIPY from APC-labelled RORgammat LBD (unknown origin) incubated for 1 hrs by binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50584380(CHEMBL5087865)
Affinity DataIC50:  10nMAssay Description:Displacement of BODIPY from APC-labelled RORgammat LBD (unknown origin) incubated for 1 hrs by binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50415761(CHEMBL5285102)
Affinity DataIC50:  10nMAssay Description:Agonist activity at human neuropeptide Y Y4 receptor expressed in HEK293T cells co-expressing CRE-controlled gene reporter firefly luciferase assesse...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50461084(CHEMBL4225088)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]UR-KK200 from human neuropeptide Y Y4 receptor expressed in CHO-mtAEQ cells co-expressing Gqi5 measured after 90 mins by scintill...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50414487(CHEMBL5269692)
Affinity DataIC50:  11nMAssay Description:Displacement of [3H]UR-MK299 from human neuropeptide Y Y1 receptor in human SK-N-MC cells measured after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM10958((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...)
Affinity DataIC50:  11.9nMAssay Description:Inhibition of rat brain AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50416545(CHEMBL5268552)
Affinity DataIC50:  12nMAssay Description:Displacement of [3H]UR-MK299 from human neuropeptide Y Y2 receptor expressed in CHO cells measured after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50584378(CHEMBL5085610)
Affinity DataIC50:  12nMAssay Description:Displacement of BODIPY from APC-labelled RORgammat LBD (unknown origin) incubated for 1 hrs by binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50414484(CHEMBL5289067)
Affinity DataIC50:  13nMAssay Description:Displacement of [3H]UR-MK299 from human neuropeptide Y Y1 receptor in human SK-N-MC cells measured after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50413830(CHEMBL5270926)
Affinity DataIC50:  13nMAssay Description:Displacement of [3H]UR-KK200 from human neuropeptide Y Y4 receptor expressed in CHO-mtAEQ cells co-expressing Gqi5 measured after 90 mins by scintill...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50415048(CHEMBL5283435)
Affinity DataIC50:  14nMAssay Description:Displacement of [3H]UR-MK299 from human neuropeptide Y Y2 receptor expressed in CHO cells measured after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50415764(CHEMBL5289290)
Affinity DataIC50:  14nMAssay Description:Displacement of [3H]UR-MK299 from human neuropeptide Y Y2 receptor expressed in CHO cells measured after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50313194(1,3alpha,8-trimethyl-1,2,3,3alpha,8,8alpha-hexahyd...)
Affinity DataIC50:  14.1nMAssay Description:Inhibition of rat plasma BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50313184(1,3alpha,8-trimethyl-1,2,3,3alpha,8,8alpha-hexahyd...)
Affinity DataIC50:  14.9nMAssay Description:Inhibition of rat plasma BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50584357(CHEMBL5084316)
Affinity DataIC50:  15nMAssay Description:Displacement of BODIPY from APC-labelled RORgammat LBD (unknown origin) incubated for 1 hrs by binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50414272(CHEMBL5278608)
Affinity DataIC50:  16nMAssay Description:Displacement of [3H]propionyl-pNPY from human neuropeptide Y Y5 receptor in human HEC-1B cells measured after 90 mins by scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50414477(CHEMBL5291188)
Affinity DataIC50:  16nMAssay Description:Displacement of [3H]propionyl-pNPY from human neuropeptide Y Y5 receptor in human HEC-1B cells measured after 90 mins by scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50461084(CHEMBL4225088)
Affinity DataIC50:  17nMAssay Description:Inverse agonist activity at RORgammat (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50584365(CHEMBL5078327)
Affinity DataIC50:  19nMAssay Description:Inverse agonist activity at RORgammat (unknown origin) transfected in human Jurkat cells assessed as inhibition of RORgammat transcriptional activity...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50414839(CHEMBL5268269)
Affinity DataIC50:  20nMAssay Description:Displacement of [3H]UR-MK299 from human neuropeptide Y Y2 receptor expressed in CHO cells measured after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50584336(CHEMBL5077074)
Affinity DataIC50:  20nMAssay Description:Displacement of BODIPY from APC-labelled RORgammat LBD (unknown origin) incubated for 1 hrs by binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50584346(CHEMBL5076525)
Affinity DataIC50:  20nMAssay Description:Displacement of BODIPY from APC-labelled RORgammat LBD (unknown origin) incubated for 1 hrs by binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50584347(CHEMBL5081603)
Affinity DataIC50:  20nMAssay Description:Displacement of BODIPY from APC-labelled RORgammat LBD (unknown origin) incubated for 1 hrs by binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50414483(CHEMBL5288554)
Affinity DataIC50:  20nMAssay Description:Displacement of [3H]UR-MK299 from human neuropeptide Y Y1 receptor in human SK-N-MC cells measured after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50414485(CHEMBL5281188)
Affinity DataIC50:  21nMAssay Description:Displacement of [3H]UR-MK299 from human neuropeptide Y Y1 receptor in human SK-N-MC cells measured after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50412731(CHEMBL5284381)
Affinity DataIC50:  22nMAssay Description:Displacement of [3H]UR-KK200 from human neuropeptide Y Y4 receptor expressed in CHO-mtAEQ cells co-expressing Gqi5 measured after 90 mins by scintill...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50413835(CHEMBL5282046)
Affinity DataIC50:  22nMAssay Description:Displacement of [3H]propionyl-pNPY from human neuropeptide Y Y5 receptor in human HEC-1B cells measured after 90 mins by scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50414480(CHEMBL5267562)
Affinity DataIC50:  23nMAssay Description:Displacement of [3H]UR-MK299 from human neuropeptide Y Y1 receptor in human SK-N-MC cells measured after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50412730(CHEMBL5279041)
Affinity DataIC50:  25nMAssay Description:Displacement of [3H]UR-KK200 from human neuropeptide Y Y4 receptor expressed in CHO-mtAEQ cells co-expressing Gqi5 measured after 90 mins by scintill...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50412732(CHEMBL5272275)
Affinity DataIC50:  25nMAssay Description:Displacement of [3H]UR-MK299 from human neuropeptide Y Y2 receptor expressed in CHO cells measured after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50415765(CHEMBL5280977)
Affinity DataIC50:  28nMAssay Description:Inhibition of RORgammat in human Jurkat cells assessed as inhibition of RORgammat transcriptional activity incubated for 10 mins by luciferase report...More data for this Ligand-Target Pair
In DepthDetails PubMed
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