Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 47 hits for monomerid = 50118239,50233301,50292722,50292723,50310540,50118239,50233301,50292722,50292723,50310540   

TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 14(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataEC50:  29nMAssay Description:Agonist activity at human P2Y14 expressed in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 14(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataEC50:  33nMAssay Description:Agonist activity at human P2Y14 expressed in rat CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataEC50:  42nMAssay Description:Agonist activity at human P2Y6 receptor expressed in 1321N1 cells assessed as IP accumulation by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataEC50:  42nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataEC50:  48nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate intracellular accumulation by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 14(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataEC50:  74nMAssay Description:Agonist activity at human P2Y14 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataEC50:  86nMAssay Description:Stimulation of phospholipase C in 1321N1 astrocytoma cells transfected with human P2Y6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataEC50:  140nMAssay Description:Agonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 14(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataEC50:  160nMAssay Description:Agonist activity at human P2Y14 receptor expressed in HEK293 cells coexpressing phospholipase C-activating Gi protein cells assessed as inhibition of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 14(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataEC50:  160nMAssay Description:Agonist activity at human recombinant P2Y14 receptor expressed in HEK293 cells assessed as [3H]inositol phosphate production by scintillation proximi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Rat)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataEC50:  200nMAssay Description:Agonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by dual-excitation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Rat)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataEC50:  200nMAssay Description:Agonist activity at rat P2Y purinoceptor 6 expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by spectrofluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataEC50:  300nMAssay Description:The compound was evaluated for agonist activity against phospholipase C coupled recombinant human P2Y purinoceptor 6 (P2Y6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataEC50:  300nMAssay Description:Antagonist activity at P2Y6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataEC50:  300nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production by scintillation pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataEC50:  300nMAssay Description:Agonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 14(Rat)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataEC50:  350nMAssay Description:Antagonist activity at rat P2Y14More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataEC50:  530nMAssay Description:Agonist activity at human P2Y6 receptor expressed in human 1321N1 cells coexpressing phospholipase C-activating Gq protein assessed as [3H]inositol p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human OGTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetRibonuclease pancreatic(Bovine)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50292723(PHOSPHORIC ACID MONO-[2-(2,4-DIOXO-3,4-DIHYDRO-2H-...)
Affinity DataKi:  7.10E+3nMAssay Description:Inhibition of bovine pancreatic RNase A by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetRibonuclease pancreatic(Bovine)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50292723(PHOSPHORIC ACID MONO-[2-(2,4-DIOXO-3,4-DIHYDRO-2H-...)
Affinity DataKi:  1.16E+4nMpH: 6.0Assay Description:Inhibition of bovine pancreatic ribonuclease A assessed as enzyme activity by spectrophotometric method pH 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetP2Y purinoceptor 4(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataEC50:  1.40E+4nMAssay Description:Agonist activity at human recombinant P2Y4 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate intracellular accumulation by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataEC50:  1.65E+4nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate intracellular accumulation by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetRibonuclease pancreatic(Bovine)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50233301(cytidine-3'-monophosphate | CHEMBL258728)
Affinity DataKi:  2.01E+4nMpH: 6.0Assay Description:Inhibition of bovine pancreatic ribonuclease A assessed as enzyme activity by spectrophotometric method pH 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetSeminal ribonuclease(Bovine)
National Hellenic Research Foundation

Curated by ChEMBL
LigandPNGBDBM50233301(cytidine-3'-monophosphate | CHEMBL258728)
Affinity DataKi:  2.79E+4nMpH: 6.0Assay Description:Inhibition of bovine seminal ribonuclease assessed as enzyme activity by spectrophotometric method at pH 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetUDP-galactopyranose mutase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Guizhou University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataKd:  3.50E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis UGM expressed in Escherichia coli BL21(DE3) assessed as dissociation constant by fluorescence polarization a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetSeminal ribonuclease(Bovine)
National Hellenic Research Foundation

Curated by ChEMBL
LigandPNGBDBM50292723(PHOSPHORIC ACID MONO-[2-(2,4-DIOXO-3,4-DIHYDRO-2H-...)
Affinity DataKi:  4.08E+4nMpH: 6.0Assay Description:Inhibition of bovine seminal ribonuclease assessed as enzyme activity by spectrophotometric method at pH 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetUDP-galactopyranose mutase(Pseudomonas aeruginosa (g-Proteobacteria))
Guizhou University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataKd:  5.40E+4nMAssay Description:Inhibition of Klebsiella pneumoniae UGM expressed in Escherichia coli BL21(DE3) assessed as dissociation constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetSeminal ribonuclease(Bovine)
National Hellenic Research Foundation

Curated by ChEMBL
LigandPNGBDBM50292722(3'-uridylic acid | 3'-UMP | CHEMBL460741)
Affinity DataKi:  6.32E+4nMpH: 6.0Assay Description:Inhibition of bovine seminal ribonuclease assessed as enzyme activity by spectrophotometric method at pH 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetBeta-galactoside alpha-2,6-sialyltransferase 1(Rat)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50310540(Phosphoric acid mono-[5-(4-amino-2-oxo-2H-pyrimidi...)
Affinity DataKi:  6.40E+4nMAssay Description:Inhibitory activity evaluated against alpha-2,6-sialyltransferase from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50310540(Phosphoric acid mono-[5-(4-amino-2-oxo-2H-pyrimidi...)
Affinity DataKi:  6.50E+4nMAssay Description:Inhibitory activity evaluated against alpha-2,3-sialyltransferase from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetRibonuclease pancreatic(Bovine)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50292722(3'-uridylic acid | 3'-UMP | CHEMBL460741)
Affinity DataKi:  7.85E+4nMpH: 6.0Assay Description:Inhibition of bovine pancreatic ribonuclease A assessed as enzyme activity by spectrophotometric method pH 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetRibonuclease pancreatic(Bovine)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50292722(3'-uridylic acid | 3'-UMP | CHEMBL460741)
Affinity DataKi:  8.20E+4nMAssay Description:Inhibition of bovine pancreatic RNase A by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataEC50: >1.00E+5nMAssay Description:Evaluated for agonist activity against phospholipase C coupled P2Y purinoceptor 1 (P2Y1) of human erythrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataEC50: >1.00E+5nMAssay Description:Evaluated for agonist activity against phospholipase C coupled recombinant human P2Y purinoceptor 2 (P2Y2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetRibonuclease pancreatic(Human)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50233301(cytidine-3'-monophosphate | CHEMBL258728)
Affinity DataKi:  1.03E+5nMAssay Description:Activity at RNase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetRibonuclease pancreatic(Bovine)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50233301(cytidine-3'-monophosphate | CHEMBL258728)
Affinity DataKi:  1.03E+5nMAssay Description:Inhibition of bovine pancreatic RNase A by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetRibonuclease pancreatic(Bovine)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50233301(cytidine-3'-monophosphate | CHEMBL258728)
Affinity DataKi:  1.03E+5nMAssay Description:Inhibition of bovine pancreatic RNase A by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetRibonuclease pancreatic(Human)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50233301(cytidine-3'-monophosphate | CHEMBL258728)
Affinity DataIC50: 3.12E+5nMAssay Description:Inhibition of RNase A by precipitation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetRibonuclease pancreatic(Bovine)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataKi:  6.47E+5nMpH: 6.0Assay Description:Inhibition of bovine pancreatic ribonuclease A assessed as enzyme activity by spectrophotometric method pH 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetRibonuclease pancreatic(Bovine)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50310540(Phosphoric acid mono-[5-(4-amino-2-oxo-2H-pyrimidi...)
Affinity DataKi:  8.44E+5nMpH: 6.0Assay Description:Inhibition of bovine pancreatic ribonuclease A assessed as enzyme activity by spectrophotometric method pH 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetSeminal ribonuclease(Bovine)
National Hellenic Research Foundation

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataKi:  1.05E+6nMpH: 6.0Assay Description:Inhibition of bovine seminal ribonuclease assessed as enzyme activity by spectrophotometric method at pH 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
University Health Network

Curated by ChEMBL
LigandPNGBDBM50310540(Phosphoric acid mono-[5-(4-amino-2-oxo-2H-pyrimidi...)
Affinity DataKi:  1.20E+6nMAssay Description:Inhibition of Methanobacterium thermoautotrophicum ODCase by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetUridine 5'-monophosphate synthase(Human)
University Health Network

Curated by ChEMBL
LigandPNGBDBM50310540(Phosphoric acid mono-[5-(4-amino-2-oxo-2H-pyrimidi...)
Affinity DataKi:  1.40E+6nMAssay Description:Inhibition of human ODCase by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSeminal ribonuclease(Bovine)
National Hellenic Research Foundation

Curated by ChEMBL
LigandPNGBDBM50310540(Phosphoric acid mono-[5-(4-amino-2-oxo-2H-pyrimidi...)
Affinity DataKi:  1.56E+6nMpH: 6.0Assay Description:Inhibition of bovine seminal ribonuclease assessed as enzyme activity by spectrophotometric method at pH 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetOrotidine-5'-phosphate decarboxylase(malaria parasite P. falciparum)
University Health Network

Curated by ChEMBL
LigandPNGBDBM50310540(Phosphoric acid mono-[5-(4-amino-2-oxo-2H-pyrimidi...)
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of Plasmodium falciparum ODCase by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed