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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Integrin alpha-4/beta-1
(Homo sapiens (Human))
Celltech Chiroscience
Curated by
ChEMBL
Ligand
BDBM50089005
((S)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
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Affinity Data
IC50: 5nM
Assay Description:
Inhibition of CS-1 peptide binding to VLA-4 expressed in Ramos cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Integrin alpha-4/beta-1
(Homo sapiens (Human))
Celltech Chiroscience
Curated by
ChEMBL
Ligand
BDBM50089005
((S)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 34nM
Assay Description:
Antagonistic activity against VLA-4 (derived from ramos cells) binding to recombinant human VCAM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Integrin alpha-4/beta-7
(Homo sapiens (Human))
Celltech Chiroscience
Curated by
ChEMBL
Ligand
BDBM50089005
((S)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
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Affinity Data
IC50: 190nM
Assay Description:
Inhibition of alpha4-beta7 integrin mediated cell adhesion
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Integrin alpha-4/beta-1
(Homo sapiens (Human))
Celltech Chiroscience
Curated by
ChEMBL
Ligand
BDBM50089005
((S)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 410nM
Assay Description:
In vitro inhibition of binding of integrin alpha4-beta1 to immobilized VCAM-1 expressed on endothelial cell surface.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human))
Celltech Chiroscience
Curated by
ChEMBL
Ligand
BDBM50089005
((S)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.00E+5nM
Assay Description:
Antagonistic activity against VLA-4 (derived from ramos cells) binding to recombinant human VCAM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Integrin alpha-IIb/beta-3
(Homo sapiens (Human))
Celltech Chiroscience
Curated by
ChEMBL
Ligand
BDBM50089005
((S)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >4.00E+5nM
Assay Description:
Antagonistic activity against VLA-4 (derived from ramos cells) binding to recombinant human VCAM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Integrin alpha-5/beta-1
(Homo sapiens (Human))
Celltech Chiroscience
Curated by
ChEMBL
Ligand
BDBM50089005
((S)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >8.00E+5nM
Assay Description:
Inhibition of alpha5-beta1 integrin mediated cell adhesion
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Integrin alpha-V/beta-3
(Homo sapiens (Human))
Celltech Chiroscience
Curated by
ChEMBL
Ligand
BDBM50089005
((S)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >8.00E+5nM
Assay Description:
Antagonistic activity against VLA-4 (derived from ramos cells) binding to recombinant human VCAM by ELISA assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI