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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
11
hits in this display
Target
Collagenase 3
(Homo sapiens (Human))
Instituto Superior TéCnico
Curated by
ChEMBL
Ligand
BDBM50273426
(CHEMBL515980 | N-(4-Phenoxybenzenesulfonyl)-N-hydr...)
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Affinity Data
IC50: 0.330nM
Assay Description:
Inhibition of MMP13
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Neutrophil collagenase
(Homo sapiens (Human))
Instituto Superior TéCnico
Curated by
ChEMBL
Ligand
BDBM50273426
(CHEMBL515980 | N-(4-Phenoxybenzenesulfonyl)-N-hydr...)
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Affinity Data
IC50: 0.400nM
Assay Description:
Inhibition of MMP8
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Instituto Superior TéCnico
Curated by
ChEMBL
Ligand
BDBM50273426
(CHEMBL515980 | N-(4-Phenoxybenzenesulfonyl)-N-hydr...)
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Affinity Data
IC50: 0.5nM
Assay Description:
Inhibition of human recombinant MMP2 transfected in mouse melanoma cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Instituto Superior TéCnico
Curated by
ChEMBL
Ligand
BDBM50273426
(CHEMBL515980 | N-(4-Phenoxybenzenesulfonyl)-N-hydr...)
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Affinity Data
IC50: 0.770nM
Assay Description:
Inhibition of MMP9
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Matrix metalloproteinase-16
(Homo sapiens (Human))
Instituto Superior TéCnico
Curated by
ChEMBL
Ligand
BDBM50273426
(CHEMBL515980 | N-(4-Phenoxybenzenesulfonyl)-N-hydr...)
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Affinity Data
IC50: 1.60nM
Assay Description:
Inhibition of MMP16
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-14
(Homo sapiens (Human))
Instituto Superior TéCnico
Curated by
ChEMBL
Ligand
BDBM50273426
(CHEMBL515980 | N-(4-Phenoxybenzenesulfonyl)-N-hydr...)
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Affinity Data
IC50: 3.90nM
Assay Description:
Inhibition of MMP14
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Stromelysin-1
(Homo sapiens (Human))
Instituto Superior T£Cnico
Curated by
ChEMBL
Ligand
BDBM50273426
(CHEMBL515980 | N-(4-Phenoxybenzenesulfonyl)-N-hydr...)
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Affinity Data
IC50: 6.70nM
Assay Description:
Inhibition of MMP3 using Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as substrate preincubated for 4 hrs measured every 15 secs for 20 mins ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Instituto Superior TéCnico
Curated by
ChEMBL
Ligand
BDBM50273426
(CHEMBL515980 | N-(4-Phenoxybenzenesulfonyl)-N-hydr...)
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Affinity Data
IC50: 59nM
Assay Description:
Inhibition of MMP1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human))
Instituto Superior TéCnico
Curated by
ChEMBL
Ligand
BDBM50273426
(CHEMBL515980 | N-(4-Phenoxybenzenesulfonyl)-N-hydr...)
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Affinity Data
IC50: 2.29E+3nM
Assay Description:
Inhibition of TACE
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Elastase
(Pseudomonas aeruginosa)
Uit - The Arctic University Of Norway
Curated by
ChEMBL
Ligand
BDBM50273426
(CHEMBL515980 | N-(4-Phenoxybenzenesulfonyl)-N-hydr...)
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Affinity Data
IC50: 8.20E+4nM
Assay Description:
Inhibition of Pseudomonas aeruginosa pseudolysin using Abz-Ala-Gly-Leu-Ala-p-nitrobenzylamide as substrate after 15 mins
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Elastase
(Pseudomonas aeruginosa)
Uit - The Arctic University Of Norway
Curated by
ChEMBL
Ligand
BDBM50273426
(CHEMBL515980 | N-(4-Phenoxybenzenesulfonyl)-N-hydr...)
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Affinity Data
IC50: 3.36E+5nM
Assay Description:
Inhibition of Pseudomonas aeruginosa pseudolysin using Mca-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys-(Dnp)-OH as substrate after 1 hr by fluorescence assay...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI