Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 12 hits in this display
IC50: 206nMAssay Description:Inhibition of full length recombinant GST-tagged human DYRK1B expressed in baculovirus using KKISGRLSPIMTEQ-NH2 as substrate after 15 minsMore data for this Ligand-Target Pair
IC50: 2.20E+3nMAssay Description:Inhibition of CLK1/4 in human T24 cells assessed as down regulation of EGFR expression after 3 days by Western blot analysisMore data for this Ligand-Target Pair
IC50: 4.20E+3nMAssay Description:Inhibition of CLK1/4 in human MDA-MB-231 cells assessed as down regulation of EGFR expression after 3 days by Western blot analysisMore data for this Ligand-Target Pair
IC50: 9.50E+3nMAssay Description:Inhibition of CLK1/4 in human T24 cells assessed as down regulation of HDAC1 expression after 3 days by Western blot analysisMore data for this Ligand-Target Pair
IC50: >2.00E+4nMAssay Description:Inhibition of CLK1/4 in human MDA-MB-231 cells assessed as down regulation of S6 kinase expression after 3 days by Western blot analysisMore data for this Ligand-Target Pair