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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 16 hits in this display   

TargetMyosin-4(Oryctolagus cuniculus)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449472(CHEBI:75379 | CHEMBL1328324)
Affinity DataIC50:  220nMAssay Description:Inhibition of rabbit skeletal muscle myosin 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyosin-2(Sus scrofa)
University Of Nevada

Curated by ChEMBL
LigandPNGBDBM50546882(CHEBI:75388 | CHEMBL1231358)
Affinity DataIC50:  400nMAssay Description:Inhibition of actin-activated porcine heart muscle myosin 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyosin-7(Sus scrofa)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449472(CHEBI:75379 | CHEMBL1328324)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of pig beta cardiac myosin 2 by NADH-coupled spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonmuscle myosin heavy chain(Gallus gallus)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449472(CHEBI:75379 | CHEMBL1328324)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of chicken non-muscle myosin 2b by NADH-coupled spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyosin-2(Bos taurus)
University Of Nevada

Curated by ChEMBL
LigandPNGBDBM50546882(CHEBI:75388 | CHEMBL1231358)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of actin-activated bovine heart muscle myosin 2 assessed as phosphate level incubated for 6 to 24 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyosin-14(Mus musculus)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449472(CHEBI:75379 | CHEMBL1328324)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of mouse non-muscle myosin 2cMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyosin-9(Homo sapiens)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449472(CHEBI:75379 | CHEMBL1328324)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human non-muscle myosin 2aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyosin-10(Homo sapiens)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449472(CHEBI:75379 | CHEMBL1328324)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of human non-muscle myosin 2bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyosin-2 heavy chain(Dictyostelium discoideum)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449472(CHEBI:75379 | CHEMBL1328324)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of RLC-phosphorylated Dictyostelium discoideum myosin 2 ATPase activity by NADH-coupled spectrophotometric analysisMore data for this Ligand-Target Pair
TargetMyosin-2 heavy chain, non muscle(Acanthamoeba castellanii)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449472(CHEBI:75379 | CHEMBL1328324)
Affinity DataIC50:  8.30E+4nMAssay Description:Inhibition of dephosphorylated Acanthamoeba non muscle myosin 2 by NADH-coupled spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUnconventional myosin-XV(Homo sapiens)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449472(CHEBI:75379 | CHEMBL1328324)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human myosin 15 by NADH-coupled spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUnconventional myosin-Va(Mus musculus)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449472(CHEBI:75379 | CHEMBL1328324)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of mouse myosin 5a by NADH-coupled spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyosin IC heavy chain(Acanthamoeba castellanii)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449472(CHEBI:75379 | CHEMBL1328324)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of dephosphorylated Acanthamoeba muscle myosin 1c by NADH-coupled spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUnconventional myosin-X(Bos taurus)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449472(CHEBI:75379 | CHEMBL1328324)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of bovine myosin x by NADH-coupled spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUnconventional myosin-Ib(Rattus norvegicus)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449472(CHEBI:75379 | CHEMBL1328324)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of rat myosin 1b by NADH-coupled spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyosin heavy chain, non-muscle(Drosophila melanogaster)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50449472(CHEBI:75379 | CHEMBL1328324)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of fruit fly non-muscle myosin 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed