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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
16
hits in this display
Target
Myosin-4
(Oryctolagus cuniculus)
Ghent University
Curated by
ChEMBL
Ligand
BDBM50449472
(CHEBI:75379 | CHEMBL1328324)
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Affinity Data
IC50: 220nM
Assay Description:
Inhibition of rabbit skeletal muscle myosin 2
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Target
Myosin-2
(Sus scrofa)
University Of Nevada
Curated by
ChEMBL
Ligand
BDBM50546882
(CHEBI:75388 | CHEMBL1231358)
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Affinity Data
IC50: 400nM
Assay Description:
Inhibition of actin-activated porcine heart muscle myosin 2
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Target
Myosin-7
(Sus scrofa)
Ghent University
Curated by
ChEMBL
Ligand
BDBM50449472
(CHEBI:75379 | CHEMBL1328324)
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Affinity Data
IC50: 1.20E+3nM
Assay Description:
Inhibition of pig beta cardiac myosin 2 by NADH-coupled spectrophotometric analysis
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Target
Nonmuscle myosin heavy chain
(Gallus gallus)
Ghent University
Curated by
ChEMBL
Ligand
BDBM50449472
(CHEBI:75379 | CHEMBL1328324)
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Affinity Data
IC50: 1.80E+3nM
Assay Description:
Inhibition of chicken non-muscle myosin 2b by NADH-coupled spectrophotometric analysis
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Target
Myosin-2
(Bos taurus)
University Of Nevada
Curated by
ChEMBL
Ligand
BDBM50546882
(CHEBI:75388 | CHEMBL1231358)
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Affinity Data
IC50: 2.30E+3nM
Assay Description:
Inhibition of actin-activated bovine heart muscle myosin 2 assessed as phosphate level incubated for 6 to 24 mins by spectrophotometric method
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Target
Myosin-14
(Mus musculus)
Ghent University
Curated by
ChEMBL
Ligand
BDBM50449472
(CHEBI:75379 | CHEMBL1328324)
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Affinity Data
IC50: 3.20E+3nM
Assay Description:
Inhibition of mouse non-muscle myosin 2c
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Target
Myosin-9
(Homo sapiens)
Ghent University
Curated by
ChEMBL
Ligand
BDBM50449472
(CHEBI:75379 | CHEMBL1328324)
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Affinity Data
IC50: 4.00E+3nM
Assay Description:
Inhibition of human non-muscle myosin 2a
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Target
Myosin-10
(Homo sapiens)
Ghent University
Curated by
ChEMBL
Ligand
BDBM50449472
(CHEBI:75379 | CHEMBL1328324)
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Affinity Data
IC50: 4.60E+3nM
Assay Description:
Inhibition of human non-muscle myosin 2b
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Target
Myosin-2 heavy chain
(Dictyostelium discoideum)
Ghent University
Curated by
ChEMBL
Ligand
BDBM50449472
(CHEBI:75379 | CHEMBL1328324)
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Affinity Data
IC50: 4.90E+3nM
Assay Description:
Inhibition of RLC-phosphorylated Dictyostelium discoideum myosin 2 ATPase activity by NADH-coupled spectrophotometric analysis
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3D Structure (crystal)
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Target
Myosin-2 heavy chain, non muscle
(Acanthamoeba castellanii)
Ghent University
Curated by
ChEMBL
Ligand
BDBM50449472
(CHEBI:75379 | CHEMBL1328324)
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Affinity Data
IC50: 8.30E+4nM
Assay Description:
Inhibition of dephosphorylated Acanthamoeba non muscle myosin 2 by NADH-coupled spectrophotometric analysis
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Target
Unconventional myosin-XV
(Homo sapiens)
Ghent University
Curated by
ChEMBL
Ligand
BDBM50449472
(CHEBI:75379 | CHEMBL1328324)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of human myosin 15 by NADH-coupled spectrophotometric analysis
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Target
Unconventional myosin-Va
(Mus musculus)
Ghent University
Curated by
ChEMBL
Ligand
BDBM50449472
(CHEBI:75379 | CHEMBL1328324)
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Affinity Data
IC50: >1.50E+5nM
Assay Description:
Inhibition of mouse myosin 5a by NADH-coupled spectrophotometric analysis
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Target
Myosin IC heavy chain
(Acanthamoeba castellanii)
Ghent University
Curated by
ChEMBL
Ligand
BDBM50449472
(CHEBI:75379 | CHEMBL1328324)
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Affinity Data
IC50: >1.50E+5nM
Assay Description:
Inhibition of dephosphorylated Acanthamoeba muscle myosin 1c by NADH-coupled spectrophotometric analysis
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Target
Unconventional myosin-X
(Bos taurus)
Ghent University
Curated by
ChEMBL
Ligand
BDBM50449472
(CHEBI:75379 | CHEMBL1328324)
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Affinity Data
IC50: >1.50E+5nM
Assay Description:
Inhibition of bovine myosin x by NADH-coupled spectrophotometric analysis
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Target
Unconventional myosin-Ib
(Rattus norvegicus)
Ghent University
Curated by
ChEMBL
Ligand
BDBM50449472
(CHEBI:75379 | CHEMBL1328324)
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Affinity Data
IC50: >1.50E+5nM
Assay Description:
Inhibition of rat myosin 1b by NADH-coupled spectrophotometric analysis
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Target
Myosin heavy chain, non-muscle
(Drosophila melanogaster)
Ghent University
Curated by
ChEMBL
Ligand
BDBM50449472
(CHEBI:75379 | CHEMBL1328324)
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Affinity Data
IC50: >2.00E+5nM
Assay Description:
Inhibition of fruit fly non-muscle myosin 2
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