Report error Found 27 Enz. Inhib. hit(s) with Target = 'HLA class II histocompatibility antigen gamma chain'
TargetHLA class II histocompatibility antigen gamma chain/Proto-oncogene tyrosine-protein kinase ROS(Human)
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 0.230nMAssay Description:Inhibition of CD74-ROS1 (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell viabilityMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen gamma chain/Proto-oncogene tyrosine-protein kinase ROS(Human)
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Inhibition of CD74-ROS1 (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell viabilityMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 810nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 930nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 950nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 980nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair