Report error Found 169 Enz. Inhib. hit(s) with Target = 'Orf1a protein'
Affinity DataKi: 280nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Affinity DataKi: 3.60E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:For the MERS-CoV 3CLpro assay, 2 μL of 0.02 μM recombinant MERS-CoV 3CL protease were mixed with serial dilutions of each compo...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:For the MERS-CoV 3CLpro assay, 2 μL of 0.02 μM recombinant MERS-CoV 3CL protease were mixed with serial dilutions of each compo...More data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:For the MERS-CoV 3CLpro assay, 2 μL of 0.02 μM recombinant MERS-CoV 3CL protease were mixed with serial dilutions of each compo...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:For the MERS-CoV 3CLpro assay, 2 μL of 0.02 μM recombinant MERS-CoV 3CL protease were mixed with serial dilutions of each compo...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Affinity DataIC50: 94nMAssay Description:For the MERS-CoV 3CLpro assay, 2 μL of 0.02 μM recombinant MERS-CoV 3CL protease were mixed with serial dilutions of each compo...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:At 48 hours prior to infection, Calu-3 2B4 cells were plated in a 96-well black-walled clear bottom plate at 5x104 cells/well. A 10 mM stock of NHC w...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:For the MERS-CoV 3CLpro assay, 2 μL of 0.02 μM recombinant MERS-CoV 3CL protease were mixed with serial dilutions of each compo...More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:For the MERS-CoV 3CLpro assay, 2 μL of 0.02 μM recombinant MERS-CoV 3CL protease were mixed with serial dilutions of each compo...More data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:For the MERS-CoV 3CLpro assay, 2 μL of 0.02 μM recombinant MERS-CoV 3CL protease were mixed with serial dilutions of each compo...More data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:For the MERS-CoV 3CLpro assay, 2 μL of 0.02 μM recombinant MERS-CoV 3CL protease were mixed with serial dilutions of each compo...More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Affinity DataIC50: 580nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Ligand InfoPurchase
Affinity DataIC50: 700nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Affinity DataIC50: 5.80E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Affinity DataIC50: 7.70E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Affinity DataIC50: 3.03E+4nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Affinity DataEC50: 1.02nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 1.35nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 1.23nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 12.3nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 1.26nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 2.51nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 80nMAssay Description:Some compounds in the 6a to 6k and 7a to 7k series were also investigated for their antiviral activity against the replication of MERS-CoV, FIPV, or ...More data for this Ligand-Target Pair
Affinity DataEC50: 50nMAssay Description:Some compounds in the 6a to 6k and 7a to 7k series were also investigated for their antiviral activity against the replication of MERS-CoV, FIPV, or ...More data for this Ligand-Target Pair
Affinity DataEC50: 530nMAssay Description:Some compounds in the 6a to 6k and 7a to 7k series were also investigated for their antiviral activity against the replication of MERS-CoV, FIPV, or ...More data for this Ligand-Target Pair
Affinity DataEC50: 210nMAssay Description:Some compounds in the 6a to 6k and 7a to 7k series were also investigated for their antiviral activity against the replication of MERS-CoV, FIPV, or ...More data for this Ligand-Target Pair
Affinity DataEC50: 40nMAssay Description:Some compounds in the 6a to 6k and 7a to 7k series were also investigated for their antiviral activity against the replication of MERS-CoV, FIPV, or ...More data for this Ligand-Target Pair
Affinity DataEC50: 900nMAssay Description:Some compounds in the 6a to 6k and 7a to 7k series were also investigated for their antiviral activity against the replication of MERS-CoV, FIPV, or ...More data for this Ligand-Target Pair
Affinity DataEC50: 500nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Affinity DataEC50: 800nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Affinity DataEC50: 3.00E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
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