Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein phosphatase 5'
TargetSerine/threonine-protein phosphatase 5(Homo sapiens (Human))TBA
LigandPNGBDBM50110690(CHEMBL17377 | FOSTRIECIN | Phosphoric acid mono-{3...)
Affinity DataIC50: >1nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay at 50 uMMore data for this Ligand-Target Pair
In DepthDetails
TargetSerine/threonine-protein phosphatase 5(Homo sapiens (Human))TBA
LigandPNGBDBM50061067(15-(3-Guanidino-propyl)-8-isobutyl-18-((1E,3E)-6-m...)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at NK2 receptor in human urinary bladder assessed as inhibition of [beta-Ala8]NKA(4-10)-induced tissue contractionsMore data for this Ligand-Target Pair
In DepthDetails
TargetSerine/threonine-protein phosphatase 5(Homo sapiens (Human))TBA
LigandPNGBDBM50110681(CHEMBL430266 | Calyculin-A)
Affinity DataIC50:  3nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay at 50 uMMore data for this Ligand-Target Pair
In DepthDetails
TargetSerine/threonine-protein phosphatase 5(Homo sapiens (Human))TBA
LigandPNGBDBM50408820(CHEMBL5268133)
Affinity DataIC50:  3.5nMAssay Description:Antagonist activity at mouse histamine H4 receptor in SK-N-MC cells assessed as inhibition of forskolin-stimulated cAMP release preincubated for 10 m...More data for this Ligand-Target Pair
In DepthDetails
TargetSerine/threonine-protein phosphatase 5(Homo sapiens (Human))TBA
LigandPNGBDBM50408822(CHEMBL5276260)
Affinity DataIC50:  4nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay at 50 uMMore data for this Ligand-Target Pair
In DepthDetails
TargetSerine/threonine-protein phosphatase 5(Homo sapiens (Human))TBA
LigandPNGBDBM50366883(TAUTOMYCIN)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at mouse histamine H4 receptor in SK-N-MC cells assessed as inhibition of forskolin-stimulated cAMP release preincubated for 10 m...More data for this Ligand-Target Pair
In DepthDetails
TargetSerine/threonine-protein phosphatase 5(Homo sapiens (Human))TBA
LigandPNGBDBM50408823(CHEMBL5276593)
Affinity DataIC50:  12nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay at 50 uMMore data for this Ligand-Target Pair
In DepthDetails
TargetSerine/threonine-protein phosphatase 5(Homo sapiens (Human))TBA
LigandPNGBDBM50090505((1R,2S,6R,7S)-2,6-Dimethyl-4,10-dioxa-tricyclo[5.2...)
Affinity DataIC50:  400nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay at 50 uMMore data for this Ligand-Target Pair
In DepthDetails
TargetSerine/threonine-protein phosphatase 5(Homo sapiens (Human))TBA
LigandPNGBDBM50090505((1R,2S,6R,7S)-2,6-Dimethyl-4,10-dioxa-tricyclo[5.2...)
Affinity DataIC50:  600nMAssay Description:Antagonist activity at rat H3 receptor expressed in human SK-N-MC cells assessed as inhibition of forskolin-induced cAMP accumulation after 6 hrsMore data for this Ligand-Target Pair
In DepthDetails
TargetSerine/threonine-protein phosphatase 5(Homo sapiens (Human))TBA
LigandPNGBDBM50607111(CHEMBL5218807)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PP5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein phosphatase 5(Homo sapiens (Human))TBA
LigandPNGBDBM50087856(CHEMBL3426913)
Affinity DataIC50: >5.00E+4nMpH: 7.0Assay Description:Inhibition of PP5 (unknown origin) using pNPP as substrate at pH 7 at 25 degC by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein phosphatase 5(Homo sapiens (Human))TBA
LigandPNGBDBM50112356(CHEMBL3609373)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human PP5 using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein phosphatase 5(Homo sapiens (Human))TBA
LigandPNGBDBM50112357(CHEMBL3609375)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human PP5 using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein phosphatase 5(Homo sapiens (Human))TBA
LigandPNGBDBM50112358(CHEMBL3609374)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human PP5 using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein phosphatase 5(Homo sapiens (Human))TBA
LigandPNGBDBM50607110(CHEMBL5219519)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PP5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine/threonine-protein phosphatase 5(Homo sapiens (Human))TBA
LigandPNGBDBM50420258(CEFSULODIN)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of phosphatase activity of human PP5 using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein phosphatase 5(Homo sapiens (Human))TBA
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of PP5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine/threonine-protein phosphatase 5(Homo sapiens (Human))TBA
LigandPNGBDBM22319((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)
Affinity DataEC50:  7.80nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay at 50 uMMore data for this Ligand-Target Pair
In DepthDetails
TargetSerine/threonine-protein phosphatase 5(Homo sapiens (Human))TBA
LigandPNGBDBM217376(DDTSRIEEVD)
Affinity DataKd:  420nMpH: 7.4 T: 2°CAssay Description:All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein phosphatase 5(Homo sapiens (Human))TBA
LigandPNGBDBM217377(GSGPTMEEVD)
Affinity DataKd:  133nMpH: 7.4 T: 2°CAssay Description:All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein phosphatase 5(Homo sapiens (Human))TBA
LigandPNGBDBM217375(DVEEM)
Affinity DataKd: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein phosphatase 5(Homo sapiens (Human))TBA
LigandPNGBDBM217372(EDASRMEEVD)
Affinity DataKd:  77nMpH: 7.4 T: 2°CAssay Description:All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein phosphatase 5(Homo sapiens (Human))TBA
LigandPNGBDBM217371(DDTSRMEEVD)
Affinity DataKd:  79nMpH: 7.4 T: 2°CAssay Description:All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein phosphatase 5(Homo sapiens (Human))TBA
LigandPNGBDBM217374(GSGPTIEEVD)
Affinity DataKd:  1.55E+3nMpH: 7.4 T: 2°CAssay Description:All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein phosphatase 5(Homo sapiens (Human))TBA
LigandPNGBDBM217373(SSGPTIEEVD)
Affinity DataKd:  1.06E+3nMpH: 7.4 T: 2°CAssay Description:All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein phosphatase 5(Homo sapiens (Human))TBA
LigandPNGBDBM50408824(CHAULMOOGRIC ACID | CHEBI:61391 | Chaulmoogric Aci...)
Affinity DataEC50:  1.30nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay at 50 uMMore data for this Ligand-Target Pair
In DepthDetails
TargetSerine/threonine-protein phosphatase 5(Homo sapiens (Human))TBA
LigandPNGBDBM217369(MEEVD)
Affinity DataKd:  140nMpH: 7.4 T: 2°CAssay Description:All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein phosphatase 5(Homo sapiens (Human))TBA
LigandPNGBDBM217370(IEEVD)
Affinity DataKd:  426nMpH: 7.4 T: 2°CAssay Description:All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed