Compile Data Set for Download or QSAR
maximum 50k data
Found 98 Enz. Inhib. hit(s) with all data for entry = 50016323
TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM431646(5-[[(2S)-1-(3-Oxo-3-[4-[5-(trifluoromethyl)pyrimid...)
Affinity DataIC50: <3nMAssay Description:Inhibition of PARP7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM434315(US10562891, Example 235 | US11008308, Example 235)
Affinity DataIC50:  3nMAssay Description:Inhibition of PARP14 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594259(CHEMBL5180081)
Affinity DataIC50:  10nMAssay Description:Inhibition of PARP14 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Homo sapiens)
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594012(CHEMBL5191676)
Affinity DataIC50:  14nMAssay Description:Inhibition of PARP11 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM431646(5-[[(2S)-1-(3-Oxo-3-[4-[5-(trifluoromethyl)pyrimid...)
Affinity DataIC50:  17nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM434254(US10562891, Example 176 | US11008308, Example 176)
Affinity DataIC50:  19nMAssay Description:Inhibition of PARP14 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM431646(5-[[(2S)-1-(3-Oxo-3-[4-[5-(trifluoromethyl)pyrimid...)
Affinity DataIC50:  37nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594258(CHEMBL5178541)
Affinity DataIC50:  76nMAssay Description:Inhibition of PARP14 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProtein mono-ADP-ribosyltransferase PARP11(Homo sapiens)
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594250(CHEMBL5207717)
Affinity DataIC50:  99nMAssay Description:Inhibition of PARP11 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594250(CHEMBL5207717)
Affinity DataIC50:  156nMAssay Description:Inhibition of PARP10 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP15(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594261(CHEMBL5190289)
Affinity DataIC50:  200nMAssay Description:Inhibition of biotinylated recombinant human PARP15 expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM434101(US10562891, Example 23 | US11008308, Example 23)
Affinity DataIC50:  300nMAssay Description:Inhibition of PARP14 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594256(CHEMBL5196898)
Affinity DataIC50:  310nMAssay Description:Displacement of [3H]NAD+ from GST-tagged PARP14 (unknown origin) incubated for 210 mins by radiometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM199181(4-[(4-Carbamoylcyclohexyl)oxy]cyclohexane-1-carbox...)
Affinity DataIC50:  330nMAssay Description:Inhibition of PARP10 (unknown origin) expressed in Escherichia coli Rosette2 (DE3)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594267(CHEMBL5189477)
Affinity DataIC50:  362nMAssay Description:Inhibition of PARP16 (unknown origin) using IRE-1 as substrate incubated for 1 hr by chemiluminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594266(CHEMBL5172255)
Affinity DataIC50:  427nMAssay Description:Inhibition of PARP16 (unknown origin) using IRE-1 as substrate incubated for 1 hr by chemiluminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50272952(CHEMBL4126054)
Affinity DataIC50:  480nMAssay Description:Inhibition of C-terminal his-tagged human PARP10 expressed in Escherichia coli Rosette2 (DE3)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594244(CHEMBL5205408)
Affinity DataIC50:  490nMAssay Description:Inhibition of PARP14 (unknown origin) expressed in bacterial expression system using histone substrate incubated for 60 mins by chemiluminescence ass...More data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP15(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594250(CHEMBL5207717)
Affinity DataIC50:  496nMAssay Description:Inhibition of PARP15 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP15(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594262(CHEMBL5187652)
Affinity DataIC50:  510nMAssay Description:Inhibition of biotinylated recombinant human PARP15 expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Homo sapiens)
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594249(CHEMBL5186007)
Affinity DataIC50:  550nMAssay Description:Inhibition of PARP11 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594255(CHEMBL5199759)
Affinity DataIC50:  580nMAssay Description:Displacement of [3H]NAD+ from GST-tagged PARP14 (unknown origin) incubated for 210 mins by radiometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594257(CHEMBL5191979)
Affinity DataIC50:  610nMAssay Description:Inhibition of PARP14 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50461016(CHEMBL4226393)
Affinity DataIC50:  710nMAssay Description:Inhibition of PARP14 MD2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594245(CHEMBL5186947)
Affinity DataIC50:  760nMAssay Description:Inhibition of PARP14 (unknown origin) expressed in bacterial expression system using histone substrate incubated for 60 mins by chemiluminescence ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594246(CHEMBL5181342)
Affinity DataIC50:  770nMAssay Description:Inhibition of PARP14 (unknown origin) expressed in bacterial expression system using histone substrate incubated for 60 mins by chemiluminescence ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50590269(CHEMBL5187963)
Affinity DataIC50:  800nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594250(CHEMBL5207717)
Affinity DataIC50:  917nMAssay Description:Inhibition of PARP14 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProtein mono-ADP-ribosyltransferase PARP15(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594263(CHEMBL5200663)
Affinity DataIC50:  970nMAssay Description:Inhibition of biotinylated recombinant human PARP15 expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594260(CHEMBL5177845)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of PARP14 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50590269(CHEMBL5187963)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of PARP14 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594254(CHEMBL5197543)
Affinity DataIC50:  1.69E+3nMAssay Description:Inhibition of PARP14 (unknown origin) incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProtein mono-ADP-ribosyltransferase PARP15(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50272952(CHEMBL4126054)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of N-terminal his-tagged human PARP15 expressed in Escherichia coli Rosette2 (DE3)More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50272952(CHEMBL4126054)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of N-terminal his-tagged human PARP2 expressed in Escherichia coli Rosette2 (DE3)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP3(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM431646(5-[[(2S)-1-(3-Oxo-3-[4-[5-(trifluoromethyl)pyrimid...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of PARP3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM431646(5-[[(2S)-1-(3-Oxo-3-[4-[5-(trifluoromethyl)pyrimid...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of PARP14 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594012(CHEMBL5191676)
Affinity DataIC50:  2.86E+3nMAssay Description:Inhibition of PARP14 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP3(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594268(CHEMBL5178746)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of recombinant human PARP3 using IRE-1 as substrate incubated for 1 hr by chemiluminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP3(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594266(CHEMBL5172255)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of recombinant human PARP3 using IRE-1 as substrate incubated for 1 hr by chemiluminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594247(CHEMBL5184823)
Affinity DataIC50:  3.64E+3nMAssay Description:Inhibition of C-terminal his-tagged human PARP10 expressed in Escherichia coli Rosette2 (DE3)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594253(CHEMBL5189956)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of PARP14 (unknown origin) incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM431646(5-[[(2S)-1-(3-Oxo-3-[4-[5-(trifluoromethyl)pyrimid...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of TNKS2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50553475(CHEMBL4741195)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of PARP10 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50272952(CHEMBL4126054)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of N-terminal his-tagged human TNKS2 expressed in Escherichia coli Rosette2 (DE3)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594249(CHEMBL5186007)
Affinity DataIC50:  8.55E+3nMAssay Description:Inhibition of PARP14 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProtein mono-ADP-ribosyltransferase PARP4(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM431646(5-[[(2S)-1-(3-Oxo-3-[4-[5-(trifluoromethyl)pyrimid...)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of PARP4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594012(CHEMBL5191676)
Affinity DataIC50:  9.28E+3nMAssay Description:Inhibition of PARP10 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP15(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM199181(4-[(4-Carbamoylcyclohexyl)oxy]cyclohexane-1-carbox...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PARP15 (unknown origin) expressed in Escherichia coli Rosette2 (DE3)More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594249(CHEMBL5186007)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TNKS1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP15(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594247(CHEMBL5184823)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of N-terminal his-tagged human PARP15 expressed in Escherichia coli Rosette2 (DE3)More data for this Ligand-Target Pair
In DepthDetails PubMed
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