Found 6 Enz. Inhib. hit(s) with Target = 'Growth factor receptor-bound protein 2' and Ligand = 'BDBM50139762'
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibitory concentration against growth factor receptor bound protein 2More data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 630nMAssay Description:Inhibition of SH2 domain of GRB2 in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of SH2 domain of GRB2 in human MDA-MB-231 cellsMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKd: 1.47nMAssay Description:Dissociation constant value against growth factor receptor bound protein 2More data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKd: 0.0750nMAssay Description:Binding affinity to SH2 domain of GRB2More data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKd: 0.0930nMAssay Description:In vitro binding affinity for Grb2 SH2 domainMore data for this Ligand-Target Pair