Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = '3-oxoacyl-[acyl-carrier-protein] synthase 3' and Ligand = 'BDBM50241313'
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
National Institute of Allergy and Infectious Diseases

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241313BDBM50241313((R)-(+)-Thiolactomycin | (5R)-4-hydroxy-3,5-dimeth...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity against KasA from Mycobacterium tuberculosis H37RvMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
National Institute of Allergy and Infectious Diseases

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241313BDBM50241313((R)-(+)-Thiolactomycin | (5R)-4-hydroxy-3,5-dimeth...)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis FabHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
National Institute of Allergy and Infectious Diseases

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241313BDBM50241313((R)-(+)-Thiolactomycin | (5R)-4-hydroxy-3,5-dimeth...)
Affinity DataIC50: 8.70E+4nMAssay Description:Inhibitory activity against FabH from Mycobacterium tuberculosis H37RvMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Escherichia coli)
Konkuk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241313BDBM50241313((R)-(+)-Thiolactomycin | (5R)-4-hydroxy-3,5-dimeth...)
Affinity DataKd:  1.21E+5nMAssay Description:Binding affinity to Escherichia coli K12 KAS 3 expressed in Escherichia coli BL21 by fluorescence quenching analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed