Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 7' and Ligand = 'BDBM21367'
Target5-hydroxytryptamine receptor 7(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21367BDBM21367(CHEMBL225284 | 6-{4-[2-(methylsulfanyl)phenyl]pipe...)
Affinity DataKi:  0.220nMAssay Description:Displacement of [3H]5-HT from human 5HT7 receptor transfected in CFO-K1 cells after 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21367BDBM21367(CHEMBL225284 | 6-{4-[2-(methylsulfanyl)phenyl]pipe...)
Affinity DataKi:  0.220nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7 receptor expressed in HEK293 cells after 1 hr by beta-countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21367BDBM21367(CHEMBL225284 | 6-{4-[2-(methylsulfanyl)phenyl]pipe...)
Affinity DataKi:  0.220nMAssay Description:Displacement of [3H]LSD from rat recombinant 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21367BDBM21367(CHEMBL225284 | 6-{4-[2-(methylsulfanyl)phenyl]pipe...)
Affinity DataKi:  0.220nMAssay Description:Displacement of [3H]LSD from rat recombinant 5-HT7 receptor expressed in HEK293 cell membranes incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21367BDBM21367(CHEMBL225284 | 6-{4-[2-(methylsulfanyl)phenyl]pipe...)
Affinity DataKi:  0.220nMAssay Description:Displacement of [3H]LSD from rat cloned 5-Hydroxytryptamine receptor 7 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21367BDBM21367(CHEMBL225284 | 6-{4-[2-(methylsulfanyl)phenyl]pipe...)
Affinity DataKi:  0.220nMAssay Description:Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21367BDBM21367(CHEMBL225284 | 6-{4-[2-(methylsulfanyl)phenyl]pipe...)
Affinity DataKi:  0.220nM ΔG°:  -57.3kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21367BDBM21367(CHEMBL225284 | 6-{4-[2-(methylsulfanyl)phenyl]pipe...)
Affinity DataKi:  53nMAssay Description:Binding affinity to human 5-HT7 receptor extracted from HEK293 cell membrane assessed as inhibition of [3H]LSD binding to 5-HT7 by measuring inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21367BDBM21367(CHEMBL225284 | 6-{4-[2-(methylsulfanyl)phenyl]pipe...)
Affinity DataEC50:  2.56E+3nMAssay Description:Activity at 5HT7 receptor assessed as relaxation of substance P-induced contraction of Dunkin-Hartley guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed