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Found 3 Enz. Inhib. hit(s) with Target = 'ALK tyrosine kinase receptor' and Ligand = 'BDBM50573595'
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chongqing Medical University

Curated by ChEMBL
LigandPNGBDBM50573595(CHEMBL4855319)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of ALK G1202R mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chongqing Medical University

Curated by ChEMBL
LigandPNGBDBM50573595(CHEMBL4855319)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chongqing Medical University

Curated by ChEMBL
LigandPNGBDBM50573595(CHEMBL4855319)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of ALK (unknown origin) preincubated for 10 mins followed by addition of substrate and ATP for 25 mins by caliper EZ reader methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed