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Found 2 Enz. Inhib. hit(s) with Target = 'Acid-sensing ion channel 3' and Ligand = 'BDBM50259583'
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50259583(3-amino-5-(biphenyl-3-yl)-N-(diaminomethylene)pyra...)
Affinity DataIC50:  490nMAssay Description:Inhibition of ASIC3 (unknown origin) assessed as inhibition of peak current by patch clamp electrophisiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid-sensing ion channel 3(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50259583(3-amino-5-(biphenyl-3-yl)-N-(diaminomethylene)pyra...)
Affinity DataIC50:  950nMAssay Description:Inhibition of rat ASIC3 assessed as inhibition of peak current by patch clamp electrophisiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed