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Found 1 Enz. Inhib. hit(s) with Target = 'Amyloid-beta precursor protein [672-711]' and Ligand = 'BDBM250505'
TargetAmyloid-beta precursor protein [672-711](Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM250505(US9464103, (6aR,7S,10aS)-10a-(4-chlorobenzenesulfo...)
Affinity DataIC50:  5.40nMpH: 7.0Assay Description:To measure γ-secretase activity, membranes were incubated at 37° C. for 1 h in 50 μL of buffer containing 20 mM Hepes (pH 7.0) and 2 mM EDT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent