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Found 4 Enz. Inhib. hit(s) with Target = 'Aromatase' and Ligand = 'BDBM9485'
TargetAromatase(Homo sapiens (Human))
University of Bari

LigandPNGBDBM9485(7-(benzyloxy)-4-(1H-imidazol-1-ylmethyl)-2H-chrome...)
Affinity DataIC50:  150nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University of Bari

LigandPNGBDBM9485(7-(benzyloxy)-4-(1H-imidazol-1-ylmethyl)-2H-chrome...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human placental microsome CYP19 using [1beta-3H] androstenedione as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University of Bari

LigandPNGBDBM9485(7-(benzyloxy)-4-(1H-imidazol-1-ylmethyl)-2H-chrome...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by liquid scintillation counting in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University of Bari

LigandPNGBDBM9485(7-(benzyloxy)-4-(1H-imidazol-1-ylmethyl)-2H-chrome...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human placental microsomal CYP19 using [1beta-3H]androstenedione substrate pre-incubated for 5 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed