Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Beta-glucuronidase' and Ligand = 'BDBM163642'
TargetBeta-glucuronidase(Escherichia coli (Enterobacteria))
University of North Carolina At Chapel Hill

LigandPNGBDBM163642(Methyl 2amino5[(3chloro4methylphenyl)carbamoyl]4me...)
Affinity DataKi:  1.90E+3nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM163642(Methyl 2amino5[(3chloro4methylphenyl)carbamoyl]4me...)
Affinity DataIC50:  1.62E+3nMAssay Description:PNPG Assay: Two ß-glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-glucuronidase(Homo sapiens (Human))
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM163642(Methyl 2amino5[(3chloro4methylphenyl)carbamoyl]4me...)
Affinity DataIC50:  1.69E+3nMAssay Description:PheG Assay: Two ß-glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorb...More data for this Ligand-Target Pair
In DepthDetails US Patent