Affinity DataKi: 240nM ΔG°: -39.3kJ/molepH: 4.5 T: 2°CAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
Affinity DataIC50: 132nMAssay Description:Inhibition of BACE2 expressed in human 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair