Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with Target = 'Bifunctional ligase/repressor BirA' and Ligand = 'BDBM161472'
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University

US Patent
LigandChemical structure of BindingDB Monomer ID 161472BDBM161472(US9108978, 2.02)
Affinity DataKi:  30nM ΔG°:  -44.7kJ/mole IC50: 203nMpH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2016
Entry Details
US Patent

TargetBifunctional ligase/repressor BirA(Escherichia coli (strain K12))
Monash University

US Patent
LigandChemical structure of BindingDB Monomer ID 161472BDBM161472(US9108978, 2.02)
Affinity DataKi:  225nM ΔG°:  -39.5kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2016
Entry Details
US Patent

TargetBifunctional ligase/repressor BirA(Escherichia coli (strain K12))
Monash University

US Patent
LigandChemical structure of BindingDB Monomer ID 161472BDBM161472(US9108978, 2.02)
Affinity DataKi:  420nM ΔG°:  -37.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2016
Entry Details
US Patent