Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 2' and Ligand = 'BDBM50566697'
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50566697(CHEMBL4862372)
Affinity DataIC50:  40nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRD2 BD2/BD1 Y113A mutant (1 to 473 residues) (unknown origin) measured after 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50566697(CHEMBL4862372)
Affinity DataIC50:  3.98E+4nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRD2 BD1/BD2 Y386A mutant (1 to 473 residues) (unknown origin) measured after 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50566697(CHEMBL4862372)
Affinity DataKd:  10nMAssay Description:Binding affinity to human partial length BRD2 BD 2 (E348 to D455 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50566697(CHEMBL4862372)
Affinity DataKd:  2.51E+4nMAssay Description:Binding affinity to human partial length BRD2 BD 1 expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed