BDBM50566697 CHEMBL4862372
SMILES CNC(=O)c1cc(cc(n1)C(O)c1ccccc1)C(=O)N[C@H]1C[C@@H]1C
InChI Key InChIKey=OJSKWCXPUVTNCF-UKOIWPHMSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 50566697
Affinity DataIC50: 2.51E+4nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRD4 BD1/BD2 Y390A mutant (1 to 477 residue) (unknown origin) measured after 30 ...More data for this Ligand-Target Pair
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKd: 3.10E+3nMAssay Description:Binding affinity to TAF1 BD 2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.98E+4nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRD2 BD1/BD2 Y386A mutant (1 to 473 residues) (unknown origin) measured after 30...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRD2 BD2/BD1 Y113A mutant (1 to 473 residues) (unknown origin) measured after 30...More data for this Ligand-Target Pair
Affinity DataIC50: 3.98E+4nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRD3 BD1/BD2 Y348A mutant (1 to 435 residues) (unknown origin) measured after 30...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRD3 BD2/BD1 Y73A mutant (1 to 435 residues) (unknown origin) measured after 30 ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.51E+4nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-FLAG-Tev-tagged BRDT BD1/BD2 Y309A (1 to 397 residues) (unknown origin) measured after 30 m...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRDT BD2/BD1 Y66A mutant (1 to 397 residues) (unknown origin) measured after 30 ...More data for this Ligand-Target Pair
Affinity DataKd: 2.51E+4nMAssay Description:Binding affinity to human partial length BRD2 BD 1 expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Binding affinity to human partial length BRD2 BD 2 (E348 to D455 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 6.31E+3nMAssay Description:Binding affinity to human partial length BRD3 BD 1 (P24 to E144 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 5nMAssay Description:Binding affinity to human partial length BRD3 BD 2 (G306 to P416 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 7.94E+3nMAssay Description:Binding affinity to human partial length BRD4 BD 1 (N44 to E168 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.30nMAssay Description:Binding affinity to human partial length BRD4 BD 2 (K333 to E460 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.51E+4nMAssay Description:Binding affinity to human partial length BRDT BD 1 (N21 to E137 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 2nMAssay Description:Binding affinity to human partial length BRDT BD 2 (K250 to E382 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from 6His-Thr tagged BRD4 BD2/BD1 Y97A mutant (1 to 477 residue) (unknown origin) measured after 30 m...More data for this Ligand-Target Pair