Found 6 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 4' and Ligand = 'BDBM50175665'
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Displacement of [125I]-TARC from human recombinant CCR4 expressed in CHO cell membranes by scintillation counting methodMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Antagonist activity at human CCR4 expressed in CHO cells by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Calcium mobilization mediated by CCR4 receptor in CEMS529 cells by FLIPRMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Displacement of [125I]TARC from human CCR4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 380nMAssay Description:Inhibition of chemotaxis of murine CCR4 transfected L1.2 cellsMore data for this Ligand-Target Pair