Found 4 Enz. Inhib. hit(s) with Target = 'Calcium-activated potassium channel subunit beta-4' and Ligand = 'BDBM50514444' TargetCalcium-activated potassium channel subunit beta-4(Homo sapiens)
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 602nMAssay Description:Inhibition of human BK alpha/beta4 channel expressed in HEK293T cells assessed as inhibition of K+ outward current fraction at -80 mV holding potenti...More data for this Ligand-Target Pair
TargetCalcium-activated potassium channel subunit beta-4(Homo sapiens)
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKd: 7.82E+5nMAssay Description:Binding affinity to NT-495 fluorophore reagent labelled human BK beta4 E104K mutant incubated for 30 mins by microscale thermophoresis assayMore data for this Ligand-Target Pair
TargetCalcium-activated potassium channel subunit beta-4(Homo sapiens)
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKd: 5.11E+5nMAssay Description:Binding affinity to NT-495 fluorophore reagent labelled human BK beta4 (45 to 166 residues) incubated for 30 mins by microscale thermophoresis assayMore data for this Ligand-Target Pair
TargetCalcium-activated potassium channel subunit beta-4(Homo sapiens)
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKd: 9.75E+5nMAssay Description:Binding affinity to NT-495 fluorophore reagent labelled human BK beta4 Q124A mutant incubated for 30 mins by microscale thermophoresis assayMore data for this Ligand-Target Pair
