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Found 3 Enz. Inhib. hit(s) with Target = 'D-amino-acid oxidase' and Ligand = 'BDBM50117763'
TargetD-amino-acid oxidase(Homo sapiens (Human))
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50117763(CHEMBL3613921 | US9505753, 5u)
Affinity DataKi:  60nMAssay Description:Competitive inhibition of recombinant human DAAO expressed in HEK cells by double reciprocal plot analysis in presence of D-serineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50117763(CHEMBL3613921 | US9505753, 5u)
Affinity DataIC50:  50nMpH: 8.5 T: 2°CAssay Description:A reliable 96-well plate D-amino acid oxidase (DAAO) assay was developed based on previously published reports (J. Biol. Chem. 277: 27782 (2002)). Br...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50117763(CHEMBL3613921 | US9505753, 5u)
Affinity DataIC50:  50nMAssay Description:Inhibition of recombinant human DAAO expressed in HEK cells using D-serine as substrate assessed as formation of alpha-keto acid, ammonia, hydrogen p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed