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Found 5 Enz. Inhib. hit(s) with Target = 'DNA gyrase subunit A/B' and Ligand = 'BDBM50366826'
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Wakunaga Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50366826(DR-3355 | Floxacin | Iquix | LEVOFLOXACIN | Levaqu...)
Affinity DataIC50:  470nMAssay Description:Inhibition of Escherichia coli DNA gyrase preincubated for 5 mins at 37 degC before addition of relaxed pBR322 as substrate by supercoiling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50366826(DR-3355 | Floxacin | Iquix | LEVOFLOXACIN | Levaqu...)
Affinity DataIC50:  2.57E+4nMAssay Description:Inhibition of Staphylococcus aureus MS5935 wild type DNA gyrase-mediated supercoiling activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50366826(DR-3355 | Floxacin | Iquix | LEVOFLOXACIN | Levaqu...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of Staphylococcus aureus wild type DNA gyraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50366826(DR-3355 | Floxacin | Iquix | LEVOFLOXACIN | Levaqu...)
Affinity DataIC50:  5.45E+5nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase S84L mutantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50366826(DR-3355 | Floxacin | Iquix | LEVOFLOXACIN | Levaqu...)
Affinity DataIC50:  2.13E+6nMAssay Description:Inhibition of quinoline-resistant Staphylococcus aureus MS5935 DNA gyrase-mediated supercoiling activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed