Found 2 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM31286' TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Broad Institute Of Harvard And Mit
Curated by ChEMBL
Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataKd: 4.80E+3nMAssay Description:Displacement of fluorescein-labeled p53 peptide from HDM2 by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Broad Institute Of Harvard And Mit
Curated by ChEMBL
Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataKd: 4.80E+3nMpH: 7.5 T: 2°CAssay Description:Test compound was incubated for 15 minutes with 30 nM peptide fluorescein-FMDYWEGLN (Fl 9mer) and 120 nM (glycine-HDM2 17-125) in assay buffer. The p...More data for this Ligand-Target Pair
